PMID- 35475094 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 14 IP - 3 DP - 2022 Mar TI - Papulonodular Mucinosis Associated With Subacute Lupus. PG - e23412 LID - 10.7759/cureus.23412 [doi] LID - e23412 AB - Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report a case of papulonodular mucinosis associated with SCLE in a middle-aged woman. On physical examination, she presented with multiple flesh-coloured asymptomatic papules and nodules on the trunk and upper extremities. A biopsy specimen taken from a nodule showed mucin within the dermis with hypodermis and perivascular lymphocytic inflammation. Considering that the proportion of patients with cutaneous lupus mucinosis who progress to systemic lupus is uncertain, we suggest following these patients closely for evidence of multisystem disease. CI - Copyright (c) 2022, Rabba et al. FAU - Rabba, Sabrine Jr AU - Rabba S Jr AD - Department of Dermatology, Ibn Rochd University Hospital, Casablanca, MAR. FAU - Hali, Fouzia Sr AU - Hali F Sr AD - Department of Dermatology, Ibn Rochd University Hospital, Casablanca, MAR. FAU - Marnissi, Farida Sr AU - Marnissi F Sr AD - Department of Pathology, Ibn Rochd University Hospital, Casablanca, MAR. FAU - Chiheb, Soumiya Sr AU - Chiheb S Sr AD - Department of Dermatology, Ibn Rochd University Hospital, Casablanca, MAR. LA - eng PT - Case Reports DEP - 20220323 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC9024385 OTO - NOTNLM OT - cutaneous lupus erythematosus OT - mucinosis OT - papulonodular mucinosis OT - subacute cutaneous lupus erythematosus OT - systemic lupus erythromatosus COIS- The authors have declared that no competing interests exist. EDAT- 2022/04/28 06:00 MHDA- 2022/04/28 06:01 PMCR- 2022/03/23 CRDT- 2022/04/27 06:20 PHST- 2022/03/22 00:00 [accepted] PHST- 2022/04/27 06:20 [entrez] PHST- 2022/04/28 06:00 [pubmed] PHST- 2022/04/28 06:01 [medline] PHST- 2022/03/23 00:00 [pmc-release] AID - 10.7759/cureus.23412 [doi] PST - epublish SO - Cureus. 2022 Mar 23;14(3):e23412. doi: 10.7759/cureus.23412. eCollection 2022 Mar.