PMID- 35494257
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2666-061X (Electronic)
IS  - 2666-061X (Linking)
VI  - 4
IP  - 2
DP  - 2022 Apr
TI  - The Minimal Clinically Important Difference, Substantial Clinical Benefit, and 
      Patient-Acceptable Symptomatic State after Medial Patellofemoral Ligament 
      Reconstruction.
PG  - e661-e678
LID - 10.1016/j.asmr.2021.12.009 [doi]
AB  - PURPOSE: To define the minimal clinically important difference (MCID), 
      substantial clinical benefit (SCB) and patient-acceptable symptomatic state 
      (PASS) for patient-reported outcome measures (PROMs) after medial patellofemoral 
      ligament reconstruction (MPFLR) and to investigate the role of preoperative, 
      demographic, and intraoperative variables for predicting achievement of these 
      thresholds. METHODS: This retrospective cohort study used a prospectively 
      maintained database of patients undergoing primary MPFLR between August 2015 and 
      December 2019. PROMs included the International Knee Documentation Committee 
      (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS), KOOS joint 
      replacement (JR), and Kujala. Anchor-based and distribution-based methods were 
      used to calculate the MCID, SCB, and PASS. Regression analyses were performed to 
      identify prognosticators for achievement of clinically significant thresholds. 
      RESULTS: 139 patients met inclusion criteria (mean age: 21.7+/- 8.2 years). At 6 
      months, the MCID values were 8.3 (KOOS-Pain) and 8.5/13.5 (Kujala); SCB values 
      were 1.4 (KOOS-Pain) and 43.7 (KOOS-QOL); and PASS values were 64.9 (IKDC), 83.3 
      (KOOS-Symptom), 76.8 (KOOS-Pain), 91.2 (KOOS-ADL), 47.5 (KOOS-Sport), 40.6 
      (KOOS-QOL), and 78.1 (KOOS-JR). At 1 year, the MCID values were 4.2 (KOOS-Pain), 
      7.2 (KOOS-ADL), 12.4 (KOOS-QOL) and 25.2 (KOOS-JR); SCB were 23.6 (IKDC), 4.2 
      (KOOS-Symptom), 19.7 (KOOS-Pain), 6.5 (KOOS-ADL), 55.0 (KOOS-Sport), 6.3 
      (KOOS-QOL), and 19.6/25.2 (KOOS-JR); and PASS were 65.5 (IKDC), 80.4 
      (KOOS-Symptom), 84.7 (KOOS-Pain), 99.3 (KOOS-ADL), 57.5 (KOOS-Sport), 53.1 
      (KOOS-QOL), and 76.3 (KOOS-JR). In regression analysis, greater age, body mass 
      index, and preoperative PROMs were negative prognosticators for achieving 
      clinically significant thresholds. Conversely, male gender increased the 
      likelihood of achieving PASS for Kujala at 6 months and KOOS-ADL at 1 year. 
      CONCLUSIONS: This study established thresholds for the MCID, SCB, and PASS at 6 
      months and 1 year after MPFLR, providing physicians an evidence-based method to 
      advise patients and assess outcomes with this surgery. Older patients and those 
      with higher preoperative outcome scores are less likely to report improvement and 
      satisfaction with MPFLR, while male patients are more likely to report some 
      satisfaction. LEVEL OF EVIDENCE: Level III, retrospective cohort study 
      (diagnosis).
CI  - (c) 2022 Published by Elsevier Inc. on behalf of the Arthroscopy Association of 
      North America.
FAU - Walsh, Justin M
AU  - Walsh JM
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Huddleston, Hailey P
AU  - Huddleston HP
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Alzein, Mohamad M
AU  - Alzein MM
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Wong, Stephanie E
AU  - Wong SE
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Forsythe, Brian
AU  - Forsythe B
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Verma, Nikhil N
AU  - Verma NN
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Cole, Brian J
AU  - Cole BJ
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
FAU - Yanke, Adam B
AU  - Yanke AB
AD  - Rush University Medical Center, Chicago, Illinois, U.S.A.
LA  - eng
PT  - Journal Article
DEP - 20220205
PL  - United States
TA  - Arthrosc Sports Med Rehabil
JT  - Arthroscopy, sports medicine, and rehabilitation
JID - 101765256
PMC - PMC9042905
EDAT- 2022/05/03 06:00
MHDA- 2022/05/03 06:01
PMCR- 2022/02/05
CRDT- 2022/05/02 06:29
PHST- 2021/04/21 00:00 [received]
PHST- 2021/12/12 00:00 [accepted]
PHST- 2022/05/02 06:29 [entrez]
PHST- 2022/05/03 06:00 [pubmed]
PHST- 2022/05/03 06:01 [medline]
PHST- 2022/02/05 00:00 [pmc-release]
AID - S2666-061X(21)00275-3 [pii]
AID - 10.1016/j.asmr.2021.12.009 [doi]
PST - epublish
SO  - Arthrosc Sports Med Rehabil. 2022 Feb 5;4(2):e661-e678. doi: 
      10.1016/j.asmr.2021.12.009. eCollection 2022 Apr.