PMID- 35494975
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220503
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 3
DP  - 2022 Mar
TI  - Diagnosed by Reversibility: Unmasking Propofol-Related Infusion Syndrome in a 
      Critically-Ill Elderly Male.
PG  - e23504
LID - 10.7759/cureus.23504 [doi]
LID - e23504
AB  - Propofol-related infusion syndrome (PRIS) is an uncommon complication resulting 
      from prolonged propofol use. Common clinical presentations include metabolic 
      acidosis, cardiac arrhythmias, and renal complications. The mortality rate is 
      high if it is not recognized in time. There is no antidote to propofol. Initial 
      treatment involves discontinuing ongoing propofol use and providing supportive 
      measures. The reversal of clinical and laboratory features upon discontinuation 
      of propofol provides a basis for retrospective diagnosis or PRIS. In severe 
      cases, ultrafiltration may be utilized.
CI  - Copyright (c) 2022, Ayele et al.
FAU - Ayele, Tewodros
AU  - Ayele T
AD  - Internal Medicine, Marshall University Joan C. Edwards School of Medicine, 
      Huntington, USA.
FAU - Ezeh, Ebubechukwu
AU  - Ezeh E
AD  - Internal Medicine, Marshall University Joan C. Edwards School of Medicine, 
      Huntington, USA.
FAU - Al-Qawasmi, Leesah
AU  - Al-Qawasmi L
AD  - Internal Medicine, Marshall University Joan C. Edwards School of Medicine, 
      Huntington, USA.
FAU - Ugonabo, Onyinye S
AU  - Ugonabo OS
AD  - Internal Medicine, Marshall University Joan C. Edwards School of Medicine, 
      Huntington, USA.
FAU - Saylor, John
AU  - Saylor J
AD  - Internal Medicine, Marshall University Joan C. Edwards School of Medicine, 
      Huntington, USA.
FAU - Dial, Larry
AU  - Dial L
AD  - Internal Medicine, Marshall University Joan C. Edwards School of Medicine, 
      Huntington, USA.
LA  - eng
PT  - Case Reports
DEP - 20220326
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9038587
OTO - NOTNLM
OT  - anesthesia
OT  - critically ill elderly patients
OT  - intensive care
OT  - metabolic acidosis
OT  - pris
OT  - propofol
OT  - propofol infusion syndrome
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/05/03 06:00
MHDA- 2022/05/03 06:01
PMCR- 2022/03/26
CRDT- 2022/05/02 06:35
PHST- 2022/03/25 00:00 [accepted]
PHST- 2022/05/02 06:35 [entrez]
PHST- 2022/05/03 06:00 [pubmed]
PHST- 2022/05/03 06:01 [medline]
PHST- 2022/03/26 00:00 [pmc-release]
AID - 10.7759/cureus.23504 [doi]
PST - epublish
SO  - Cureus. 2022 Mar 26;14(3):e23504. doi: 10.7759/cureus.23504. eCollection 2022 
      Mar.