PMID- 35498435
OWN - NLM
STAT- MEDLINE
DCOM- 20220503
LR  - 20220728
IS  - 1664-2392 (Print)
IS  - 1664-2392 (Electronic)
IS  - 1664-2392 (Linking)
VI  - 13
DP  - 2022
TI  - Rehabilitation of Individuals With Diabetes Mellitus: Focus on Diabetic Myopathy.
PG  - 869921
LID - 10.3389/fendo.2022.869921 [doi]
LID - 869921
AB  - Diabetes mellitus (DM) is a chronic metabolic disease characterized by high blood 
      glucose levels, causing serious damage to the cardiovascular, respiratory, renal 
      and other systems. The prevalence of type 2 diabetes mellitus (T2DM) was 6.28% in 
      2017, considering all age groups worldwide (prevalence rate of 6,059 cases per 
      100,000), and its global prevalence is projected to increase to 7,079 cases per 
      100,000 by 2030. Furthermore, these individuals are often affected by diabetic 
      myopathy, which is the failure to preserve muscle mass and function in the course 
      of DM. This happens in type 1 diabetes mellitus (T1DM) and T2DM. As skeletal 
      muscle plays a key role in locomotion and glucose homeostasis, diabetic myopathy 
      may contribute to additional complications of the disease. In addition, chronic 
      hyperglycemia is associated with lung functional changes seen in patients with 
      DM, such as reduced lung volumes and compliance, inspiratory muscle strength, and 
      lung elastic recoil. Thus, the weakness of the inspiratory muscles, a consequence 
      of diabetic myopathy, can influence exercise tolerance. Thus, moderate strength 
      training in T2DM can contribute to the gain of peripheral muscle strength. 
      Although the literature is robust on the loss of mass and consequent muscle 
      weakness in diabetic myopathy, triggering pathophysiological factors, the impact 
      on functional capacity, as well as the prescription of physical exercise for this 
      condition deserves to be further explored. This review aims to explore the 
      consequences of diabetic myopathy and its implication in rehabilitation from 
      prescription to safety in the practice of physical exercises for these 
      individuals.
CI  - Copyright (c) 2022 Bassi-Dibai, Santos-de-Araujo, Dibai-Filho, de Azevedo, Goulart, 
      Luz, Burke, Garcia-Araujo and Borghi-Silva.
FAU - Bassi-Dibai, Daniela
AU  - Bassi-Dibai D
AD  - Postgraduate Program in Environment, Universidade Ceuma, Sao Luis, Brazil.
FAU - Santos-de-Araujo, Aldair Darlan
AU  - Santos-de-Araujo AD
AD  - Postgraduate Program in Physical Therapy, Universidade Federal de Sao Carlos, Sao 
      Carlos, Brazil.
FAU - Dibai-Filho, Almir Vieira
AU  - Dibai-Filho AV
AD  - Postgraduate Program in Adult Health, Universidade Federal do Maranhao, Sao Luis, 
      Brazil.
FAU - de Azevedo, Lisiane Fernanda Simeao
AU  - de Azevedo LFS
AD  - Postgraduate Program in Environment, Universidade Ceuma, Sao Luis, Brazil.
FAU - Goulart, Cassia da Luz
AU  - Goulart CDL
AD  - Postgraduate Program in Physical Therapy, Universidade Federal de Sao Carlos, Sao 
      Carlos, Brazil.
FAU - Luz, Gabriela Costa Pontes
AU  - Luz GCP
AD  - Department of Physical Therapy, Universidade Ceuma, Sao Luis, Brazil.
FAU - Burke, Patrick Rademaker
AU  - Burke PR
AD  - Department of Medicine, Universidade Federal do Maranhao, Pinheiro, Brazil.
FAU - Garcia-Araujo, Adriana Sanches
AU  - Garcia-Araujo AS
AD  - Department of Physical Therapy, Universidade Federal de Sao Carlos, Sao Carlos, 
      Brazil.
FAU - Borghi-Silva, Audrey
AU  - Borghi-Silva A
AD  - Postgraduate Program in Physical Therapy, Universidade Federal de Sao Carlos, Sao 
      Carlos, Brazil.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20220414
PL  - Switzerland
TA  - Front Endocrinol (Lausanne)
JT  - Frontiers in endocrinology
JID - 101555782
SB  - IM
MH  - *Diabetes Mellitus, Type 1/complications
MH  - *Diabetes Mellitus, Type 2
MH  - Exercise Tolerance
MH  - Humans
MH  - Muscle Strength/physiology
MH  - *Muscular Diseases
PMC - PMC9047902
OTO - NOTNLM
OT  - cardiometabolic rehabilitation
OT  - diabetes mellitus
OT  - diabetic myopathy
OT  - muscular strength
OT  - physical exercise
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/05/03 06:00
MHDA- 2022/05/04 06:00
PMCR- 2022/01/01
CRDT- 2022/05/02 07:11
PHST- 2022/02/05 00:00 [received]
PHST- 2022/03/21 00:00 [accepted]
PHST- 2022/05/02 07:11 [entrez]
PHST- 2022/05/03 06:00 [pubmed]
PHST- 2022/05/04 06:00 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fendo.2022.869921 [doi]
PST - epublish
SO  - Front Endocrinol (Lausanne). 2022 Apr 14;13:869921. doi: 
      10.3389/fendo.2022.869921. eCollection 2022.