PMID- 35499150 OWN - NLM STAT- MEDLINE DCOM- 20220908 LR - 20220919 IS - 1552-3799 (Electronic) IS - 1054-7738 (Print) IS - 1054-7738 (Linking) VI - 31 IP - 7 DP - 2022 Sep TI - Efficacy and Safety of Acupuncture and or Moxibustion for Managing Primary Dysmenorrhea: A Systematic Review and Meta-Analysis. PG - 1362-1375 LID - 10.1177/10547738221086984 [doi] AB - Acupuncture and moxibustion have been accepted as add-on options for primary dysmenorrhea (PD); however, the clinical evidence is still inadequate. We searched AMED, CENTRAL, EMBASE, PubMed, Web of Science, CBM, CNKI, VIP, Wangfang database, ANZCTR, ClinicalTrials.gov, and the WHO ICTRP, from their inception to February 2021. The pooled analysis of 13 RCTs with 675 participants for VAS showed that acupuncture and moxibustion were more effective in managing PD than the control group with the MD of -1.93 (95% CI [-2.80, -1.06] and -2.67 (95% CI [-4.96, -0.38]). With the CMSS, seven studies with 487 participants showed that these modalities were more effective than the control group with the MD of -7.58 (95% CI [-10.97, -4.19]) and -3.78 (95% CI [-6.90, -0.66]). The findings indicated that acupuncture and moxibustion could relieve pain effectively and has fewer adverse events (AEs) in managing PD. FAU - Liu, Weiting AU - Liu W AUID- ORCID: 0000-0001-6936-8872 AD - Edith Cowan University, Perth, WA, Australia. FAU - Wang, Carol Chunfeng AU - Wang CC AD - Edith Cowan University, Perth, WA, Australia. FAU - Lee, Khui Hung AU - Lee KH AUID- ORCID: 0000-0001-5906-4664 AD - Edith Cowan University, Perth, WA, Australia. FAU - Ma, Xiaopeng AU - Ma X AD - Shanghai Research Institute of Acupuncture and Meridian, China. FAU - Kang, Timothy Leen AU - Kang TL AD - Institute of Chinese Acuology, Perth, WA, Australia. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Systematic Review DEP - 20220502 PL - United States TA - Clin Nurs Res JT - Clinical nursing research JID - 9208508 MH - *Acupuncture Therapy/adverse effects MH - Dysmenorrhea/etiology/therapy MH - Female MH - Humans MH - *Moxibustion/adverse effects PMC - PMC9449440 OTO - NOTNLM OT - acupuncture OT - moxibustion OT - nursing OT - primary dysmenorrhea OT - review COIS- Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2022/05/03 06:00 MHDA- 2022/09/09 06:00 PMCR- 2022/09/07 CRDT- 2022/05/02 07:24 PHST- 2022/05/03 06:00 [pubmed] PHST- 2022/09/09 06:00 [medline] PHST- 2022/05/02 07:24 [entrez] PHST- 2022/09/07 00:00 [pmc-release] AID - 10.1177_10547738221086984 [pii] AID - 10.1177/10547738221086984 [doi] PST - ppublish SO - Clin Nurs Res. 2022 Sep;31(7):1362-1375. doi: 10.1177/10547738221086984. Epub 2022 May 2.