PMID- 35505631
OWN - NLM
STAT- MEDLINE
DCOM- 20230915
LR  - 20230915
IS  - 1532-5040 (Electronic)
IS  - 0959-3985 (Linking)
VI  - 39
IP  - 10
DP  - 2023 Oct 3
TI  - Interferential current intensity influences the hypoalgesic response in healthy 
      subjects under mechanically-induced pain: A randomized controlled trial.
PG  - 2087-2098
LID - 10.1080/09593985.2022.2068095 [doi]
AB  - BACKGROUND: Interferential current (IFC) is a non-pharmacological therapy often 
      used to reduce pain intensity. However, there is no scientific evidence of the 
      biological effects of the adjustment of IFC intensity of stimulation. OBJECTIVE: 
      To investigate whether the adjustment of IFC intensity influences pain on 
      cutaneous sensory threshold (CST), pressure pain threshold (PPT) and pain 
      intensity in healthy subjects under mechanically induced pain. METHODS: This is a 
      placebo-controlled randomized trial. One hundred and two healthy university 
      students blinded to intervention were randomized using opaque sealed envelopes to 
      the following groups: 1) sensory IFC (n = 24); 2) fixed motor IFC (n = 26); 3) 
      adjusted motor IFC (n = 27); and 4) placebo IFC (n = 25). After 40 minutes of 
      stimulation or placebo, subjects were evaluated by an investigator blinded to 
      group allocation. CST (von Frey filaments), PPT (algometry), and pain intensity 
      (11-point numerical scale) were measured. RESULTS: Adjusted motor IFC promoted a 
      significant reduction of CST (hand: mean difference (MD) = 2.39, confidence 
      intervals (CI) = 1.39-3.38; and forearm: MD = 3.01, CI = 2.87-3.14) compared to 
      placebo. Adjusted motor IFC increased PPT significantly (hand: MD = 27.59, 
      CI = 26.80-28.37; and forearm: MD = 34, CI = 25.74-42.25) when compared to 
      placebo. Adjusted motor IFC reduced pain intensity by 4.01 points 
      (CI = 3.64-4.55) when compared to placebo. No adverse events were observed. 
      CONCLUSIONS: Adjusted motor IFC intensity increased PPT and CST and also reduced 
      pain intensity in healthy subjects under mechanically induced pain.
FAU - Menezes, Mayara Alves
AU  - Menezes MA
AD  - Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, 
      Sergipe, Brazil.
FAU - Mendonca Araujo, Fernanda
AU  - Mendonca Araujo F
AD  - Physiological Sciences Graduate Program, Federal University of Sergipe, Sao 
      Cristovao, Sergipe, Brazil.
FAU - Lima, Lucas Vasconcelos
AU  - Lima LV
AD  - Department of Psychology, McGill University, 2001 Avenue McGill College, 
      Montreal, QC, Canada.
FAU - Souza, Thiago Abner Santos
AU  - Souza TAS
AD  - Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, 
      Sergipe, Brazil.
FAU - Carvalho, Elyson Adan Nunes
AU  - Carvalho EAN
AD  - Department of Electrical Engineering, Graduate Program in Electrical Engineering, 
      Federal University of Sergipe, Sao Cristovao, Brazil.
FAU - Melo DeSantana, Josimari
AU  - Melo DeSantana J
AD  - Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, 
      Sergipe, Brazil.
AD  - Physiological Sciences Graduate Program, Federal University of Sergipe, Sao 
      Cristovao, Sergipe, Brazil.
AD  - Department of Physical Therapy, Federal University of Sergipe, Brazil.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20220503
PL  - England
TA  - Physiother Theory Pract
JT  - Physiotherapy theory and practice
JID - 9015520
SB  - IM
MH  - Humans
MH  - Healthy Volunteers
MH  - *Pain/etiology
MH  - Pain Threshold
MH  - Pain Measurement
MH  - Hand
MH  - *Transcutaneous Electric Nerve Stimulation
OTO - NOTNLM
OT  - Interferential current
OT  - current intensity
OT  - electric stimulation therapy
OT  - hypoalgesia
OT  - pain measurement
EDAT- 2022/05/05 06:00
MHDA- 2023/09/15 06:42
CRDT- 2022/05/04 01:53
PHST- 2023/09/15 06:42 [medline]
PHST- 2022/05/05 06:00 [pubmed]
PHST- 2022/05/04 01:53 [entrez]
AID - 10.1080/09593985.2022.2068095 [doi]
PST - ppublish
SO  - Physiother Theory Pract. 2023 Oct 3;39(10):2087-2098. doi: 
      10.1080/09593985.2022.2068095. Epub 2022 May 3.