PMID- 35507840
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221202
IS  - 2765-0189 (Print)
IS  - 2765-0235 (Electronic)
IS  - 2765-0189 (Linking)
VI  - 35
IP  - 12
DP  - 2022 Dec
TI  - Age quadratically affects intestinal calcium and phosphorus transporter gene 
      expression in broiler chickens.
PG  - 1921-1928
LID - 10.5713/ab.22.0058 [doi]
AB  - OBJECTIVE: This research aimed to evaluate the effects of age on growth, tibia 
      development, and intestinal calcium (Ca) and phosphorus (P) transporter gene 
      expressions in broiler chickens. METHODS: A total of 224 male Arbor Acres 
      broilers were fed with nutrient-adequate diets and reared in eight cages (28 
      broilers per cage). Eight broilers (one broiler per cage) were selected and 
      killed at 5, 10, 15, 20, 25, 30, 35, and 40 days of age, respectively. RESULTS: 
      Body weight continuously increased with age of broiler chickens from 5 to 40 
      days. The bone weight, ash weight, diameter, and length of the tibia also 
      increased with broiler age. By contrast, the tibia ash, Ca, and P percentages 
      quadratically changed with age (p<0.001), and the highest values of mineral 
      contents were observed at 20, 25, and 25 days of age, respectively. The mRNA 
      abundances of calcium-binding protein 28-kDa (CaBP-D28k), sodium-calcium 
      exchanger 1 (NCX1), and plasma membrane ATPase 1b (PMCA1b) increased from 5 to 25 
      days and then decreased up to 40 days. Similar results were noted in the mRNA 
      abundances of IIb sodium-phosphate cotransporter (NaPi-IIb), inorganic phosphate 
      transporter 1 (PiT-1), inorganic phosphate transporter 2 (PiT-2), nuclear vitamin 
      D receptor (nVDR), and membrane vitamin D receptor (mVDR). The mRNA abundances of 
      Ca and P transporters and VDRs were the highest at 25 days of age. CONCLUSION: 
      These data indicate that age quadratically affects intestinal Ca and P 
      transporter gene expression and mineral absorption capacity in broiler chickens.
FAU - Lv, Xianliang
AU  - Lv X
AD  - College of Animal Science and Technology, Henan Agricultural University, 
      Zhengzhou 450046, China.
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Hao, Junfang
AU  - Hao J
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Wu, Lihua
AU  - Wu L
AD  - College of Animal Science and Technology, Henan Agricultural University, 
      Zhengzhou 450046, China.
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Liu, Mengyuan
AU  - Liu M
AD  - College of Animal Science and Technology, Henan Agricultural University, 
      Zhengzhou 450046, China.
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - He, Lei
AU  - He L
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
AD  - College of Life Sciences, Henan Normal University, Xinxiang 453007, China.
FAU - Qiao, Yingying
AU  - Qiao Y
AD  - Department of Biochemistry and Biotechnology, Sumy National Agrarian University, 
      Sumy 40000, Ukraine.
FAU - Cui, Yanyan
AU  - Cui Y
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Wang, Guan
AU  - Wang G
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Zhang, Chunmei
AU  - Zhang C
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Qu, Hongxia
AU  - Qu H
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
FAU - Han, Jincheng
AU  - Han J
AD  - Department of Animal Science, College of Biology and Food, Shangqiu Normal 
      University, Shangqiu 476000, China.
LA  - eng
GR  - 32072753/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20220502
PL  - Korea (South)
TA  - Anim Biosci
JT  - Animal bioscience
JID - 101774366
PMC - PMC9659444
OTO - NOTNLM
OT  - Age
OT  - Broiler Chicken
OT  - CaBP-D28k
OT  - NaPi-IIb
OT  - PMCA1b
OT  - PiT-1
COIS- CONFLICT OF INTEREST We certify that there is no conflict of interest with any 
      financial organization regarding the material discussed in the manuscript.
EDAT- 2022/05/05 06:00
MHDA- 2022/05/05 06:01
PMCR- 2022/12/01
CRDT- 2022/05/04 16:00
PHST- 2022/02/16 00:00 [received]
PHST- 2022/04/28 00:00 [accepted]
PHST- 2022/05/05 06:00 [pubmed]
PHST- 2022/05/05 06:01 [medline]
PHST- 2022/05/04 16:00 [entrez]
PHST- 2022/12/01 00:00 [pmc-release]
AID - ab.22.0058 [pii]
AID - ab-22-0058 [pii]
AID - 10.5713/ab.22.0058 [doi]
PST - ppublish
SO  - Anim Biosci. 2022 Dec;35(12):1921-1928. doi: 10.5713/ab.22.0058. Epub 2022 May 2.