PMID- 35507951
OWN - NLM
STAT- MEDLINE
DCOM- 20220506
LR  - 20230831
IS  - 2380-0194 (Electronic)
IS  - 2380-0186 (Linking)
VI  - 35
IP  - 4
DP  - 2022 May 1
TI  - Cervical Disc Replacement for Radiculopathy Versus Myeloradiculopathy: An MCID 
      Analysis.
PG  - 170-175
LID - 10.1097/BSD.0000000000001313 [doi]
AB  - STUDY DESIGN: Retrospective cohort study. OBJECTIVES: The aim was to compare the 
      minimally clinically important difference (MCID) across multiple patient-reported 
      outcomes (PROs) in patients undergoing cervical disc replacement (CDR) for 
      cervical spondylotic radiculopathy versus myeloradiculopathy. SUMMARY OF 
      BACKGROUND DATA: To date, a limited number of studies have demonstrated mostly 
      similar results in patients with cervical spondylotic radiculopathy or 
      myeloradiculopathy undergoing CDR. However, each of these previous studies have 
      focused on statistically significant differences, which may not correlate with 
      patient perceived improvements in outcomes or success. METHODS: Patients who 
      underwent 1 or 2-level CDR with radiculopathy versus myeloradiculopathy were 
      identified, and prospectively collected data was retrospectively reviewed. 
      Demographic variables, preoperative diagnosis, and operative variables were 
      collected for each patient. The following PROs were prospectively collected: Neck 
      Disability Index (NDI), visual analog scale (VAS)-Neck, VAS-Arm, Short Form-12 
      Health Survey (SF-12) Physical Component Score (PCS), SF-12 Mental Component 
      Score (MCS), PROMIS Physical Function (PF). An MCID analysis of PROs for each 
      diagnosis group was performed and the percentage of patients achieving the MCID 
      was compared between the two diagnosis groups. RESULTS: Eight-five patients, of 
      which 56% had radiculopathy and 44% had myeloradiculopathy. MCID analysis 
      demonstrated that at 6-week, 12-week, and final postoperative follow-up there was 
      no significant difference in the percentage of patients with radiculopathy or 
      myeloradiculopathy achieving the MCID for each PRO assessed. In both diagnosis 
      groups the percentage of patients achieving the MCID for each PRO continued to 
      increase from the 6-week to final postoperative follow-up except for the SF-12 
      MCS in patients with myeloradiculopathy. CONCLUSIONS: The percentage of patients 
      achieving the MCID was not significantly different at each postoperative period 
      assessed in the radiculopathy and myeloradiculopathy groups treated with CDR. In 
      addition, the percentage of patients achieving the MCID continued to increase 
      from 6 weeks to final follow-up in both groups for almost all PROs assessed.
CI  - Copyright (c) 2022 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Alluri, Ram K
AU  - Alluri RK
AD  - Hospital for Special Surgery.
FAU - Vaishnav, Avani S
AU  - Vaishnav AS
AD  - Hospital for Special Surgery.
FAU - Sivaganesan, Ahilan
AU  - Sivaganesan A
AD  - Hospital for Special Surgery.
FAU - Albert, Todd J
AU  - Albert TJ
AD  - Hospital for Special Surgery.
AD  - Weill Cornell Medical College, New York, NY.
FAU - Huang, Russel C
AU  - Huang RC
AD  - Hospital for Special Surgery.
AD  - Weill Cornell Medical College, New York, NY.
FAU - Qureshi, Sheeraz A
AU  - Qureshi SA
AD  - Hospital for Special Surgery.
AD  - Weill Cornell Medical College, New York, NY.
LA  - eng
PT  - Journal Article
DEP - 20220418
PL  - United States
TA  - Clin Spine Surg
JT  - Clinical spine surgery
JID - 101675083
SB  - IM
MH  - Cervical Vertebrae/surgery
MH  - Humans
MH  - *Radiculopathy/surgery
MH  - Retrospective Studies
MH  - *Spinal Cord Diseases/surgery
MH  - *Spondylosis/surgery
MH  - Treatment Outcome
COIS- The authors declare no conflict of interest.
EDAT- 2022/05/05 06:00
MHDA- 2022/05/07 06:00
CRDT- 2022/05/04 17:32
PHST- 2022/01/24 00:00 [received]
PHST- 2022/03/01 00:00 [accepted]
PHST- 2022/05/04 17:32 [entrez]
PHST- 2022/05/05 06:00 [pubmed]
PHST- 2022/05/07 06:00 [medline]
AID - 01933606-202205000-00007 [pii]
AID - 10.1097/BSD.0000000000001313 [doi]
PST - ppublish
SO  - Clin Spine Surg. 2022 May 1;35(4):170-175. doi: 10.1097/BSD.0000000000001313. 
      Epub 2022 Apr 18.