PMID- 35514179
OWN - NLM
STAT- Publisher
LR  - 20231020
IS  - 1563-5279 (Electronic)
IS  - 0020-7454 (Linking)
VI  - 133
IP  - 11
DP  - 2023 Dec
TI  - Clinical outcome in an infant with anti-NMDA receptor encephalitis: case report 
      and literature review.
PG  - 1247-1251
LID - 10.1080/00207454.2022.2074847 [doi]
AB  - Anti N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disease 
      that often presents with various neurological and neuropsychiatric symptoms. 
      Although most reported cases occur in children, only a limited number of studies 
      on children are available. The subject of this case report is an 8-month-old 
      female who presented with fever, vomiting, and seizure. She was diagnosed with 
      encephalitis and treated with acyclovir. After 21 days, she showed irritability, 
      seizure, orolingual-facial dyskinesias, choreodystonic movements, hemiparesis, 
      dysphagia, strabismus, lack of interest in light and objects. Clinical signs, 
      neuroimaging findings, and serum analysis of anti-NMDAR antibodies confirmed the 
      diagnosis of anti-NMDAR encephalitis. After the first line of treatment, she 
      showed full recovery. We update the infants with anti-NMDAR encephalitis in the 
      literature. Clinical outcomes suggest that patients with anti-NMDAR encephalitis 
      are mostly poor in the infants, excluding our case. We propose that early and 
      appropriate treatments are critical for timely diagnosis and rapid improvement.
FAU - Cavusoglu, Dilek
AU  - Cavusoglu D
AUID- ORCID: 0000-0003-4924-5300
AD  - Department of Pediatric Neurology, Faculty of Medicine, Afyonkarahisar Health 
      Sciences University, Afyon, Turkey.
FAU - Ozer Gokaslan, Cigdem
AU  - Ozer Gokaslan C
AUID- ORCID: 0000-0001-5345-1735
AD  - Department of Radiology, Faculty of Medicine, Afyonkarahisar Health Sciences 
      University, Afyon, Turkey.
FAU - Olgac Dundar, Nihal
AU  - Olgac Dundar N
AUID- ORCID: 0000-0002-5902-3501
AD  - Department of Pediatric Neurology, Faculty of Medicine, Izmir Katip Celebi 
      University, Izmir, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20220511
PL  - England
TA  - Int J Neurosci
JT  - The International journal of neuroscience
JID - 0270707
SB  - IM
OTO - NOTNLM
OT  - Anti-NMDAR encephalitis
OT  - infant
OT  - neuroimage
OT  - outcome
EDAT- 2022/05/07 06:00
MHDA- 2022/05/07 06:00
CRDT- 2022/05/06 03:12
PHST- 2022/05/07 06:00 [pubmed]
PHST- 2022/05/07 06:00 [medline]
PHST- 2022/05/06 03:12 [entrez]
AID - 10.1080/00207454.2022.2074847 [doi]
PST - ppublish
SO  - Int J Neurosci. 2023 Dec;133(11):1247-1251. doi: 10.1080/00207454.2022.2074847. 
      Epub 2022 May 11.