PMID- 35516287
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230916
IS  - 2046-2069 (Electronic)
IS  - 2046-2069 (Linking)
VI  - 10
IP  - 73
DP  - 2020 Dec 17
TI  - Determination of common organophosphorus pesticides in the blood of children with 
      acute leukaemia using a double-solvent system as a novel extractant for 
      dispersive liquid-liquid microextraction.
PG  - 44736-44742
LID - 10.1039/d0ra09303c [doi]
AB  - In this research, a new mode of dispersive liquid-liquid microextraction based on 
      a double-solvent system (DLLME-DSS) was developed for the extraction and 
      preconcentration of organophosphorus pesticides (OPPs) in the blood of children 
      with acute leukaemia prior to determination by high-performance liquid 
      chromatography-ultraviolet detection (HPLC-UV). In the present method, two long 
      normal chain alcohols are mixed in a particular ratio, and then injected into the 
      sample solution, which is magnetically stirred. In this case, the mixture of the 
      two alcohols changes to a new aggregate extractant. This new double-solvent is 
      used as an extractant, which has a higher extraction power than any of its 
      components alone. Under the optimum conditions, the calibration graph was linear 
      in the rage of 3-600 mug L(-1) with detection limits of 1 to 2 mug L(-1). Relative 
      standard deviations (RSDs) including intra-day and inter-day of the method based 
      on 7 replicate determinations of 100.0 mug L(-1) for each analyte were in the 
      range of 2.9-4.7% and 3.8-6.1%, respectively. The results proved that DLLME-DSS 
      is a sensitive, very simple, inexpensive, environmentally friendly, rapid and 
      efficient method for the preconcentration of trace amounts of OPPs in blood 
      samples.
CI  - This journal is (c) The Royal Society of Chemistry.
FAU - Akramipour, Reza
AU  - Akramipour R
AD  - School of Medical, Kermanshah University of Medical Sciences Kermanshah Iran.
AD  - Clinical Research Development Center, Mohammad Kermanshahi Hospital, Kermanshah 
      University of Medical Sciences Kermanshah Iran.
FAU - Golpayegani, Mohammad Reza
AU  - Golpayegani MR
AD  - School of Medical, Kermanshah University of Medical Sciences Kermanshah Iran.
AD  - Clinical Research Development Center, Mohammad Kermanshahi Hospital, Kermanshah 
      University of Medical Sciences Kermanshah Iran.
FAU - Sedighi, Mostafa
AU  - Sedighi M
AD  - School of Medical, Kermanshah University of Medical Sciences Kermanshah Iran.
AD  - Clinical Research Development Center, Mohammad Kermanshahi Hospital, Kermanshah 
      University of Medical Sciences Kermanshah Iran.
FAU - Fattahi, Farshad
AU  - Fattahi F
AD  - Clinical Research Development Center, Mohammad Kermanshahi Hospital, Kermanshah 
      University of Medical Sciences Kermanshah Iran.
FAU - Fattahi, Nazir
AU  - Fattahi N
AUID- ORCID: 0000-0002-6750-7004
AD  - Research Center for Environmental Determinants of Health (RCEDH), Health 
      Institute, Kermanshah University of Medical Sciences Kermanshah Iran 
      n.fattahi@kums.ac.ir +988338263048 +989183364311.
LA  - eng
PT  - Journal Article
DEP - 20201218
PL  - England
TA  - RSC Adv
JT  - RSC advances
JID - 101581657
PMC - PMC9058556
COIS- There are no conflicts to declare.
EDAT- 2020/12/18 00:00
MHDA- 2020/12/18 00:01
PMCR- 2020/12/18
CRDT- 2022/05/06 05:41
PHST- 2020/11/01 00:00 [received]
PHST- 2020/12/07 00:00 [accepted]
PHST- 2022/05/06 05:41 [entrez]
PHST- 2020/12/18 00:00 [pubmed]
PHST- 2020/12/18 00:01 [medline]
PHST- 2020/12/18 00:00 [pmc-release]
AID - d0ra09303c [pii]
AID - 10.1039/d0ra09303c [doi]
PST - epublish
SO  - RSC Adv. 2020 Dec 18;10(73):44736-44742. doi: 10.1039/d0ra09303c. eCollection 
      2020 Dec 17.