PMID- 35516662
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2249-4863 (Print)
IS  - 2278-7135 (Electronic)
IS  - 2249-4863 (Linking)
VI  - 11
IP  - 4
DP  - 2022 Apr
TI  - A case of "very" very late stent thrombosis: More than 12 years after DES.
PG  - 1545-1548
LID - 10.4103/jfmpc.jfmpc_1533_21 [doi]
AB  - A rare but possibly catastrophic consequence of drug-eluting stents (DES) is very 
      late stent thrombosis. We report a case of 74-year-old male who sustained a ST 
      elevation myocardial infarction (STEMI) 12 years after initial Paclitaxel eluting 
      stent implantation (PES). This is the longest time between stent placement and 
      the development of an acute coronary event due to very late stent thrombosis that 
      we are aware of (VLST). The implications for prognosis and therapy are 
      significant because they highlight the uncertainty around the recommended 
      duration of antiplatelet medication in patients with DES. Clinicians face 
      challenges in treating those patients particularly when competing medical 
      conditions demand the discontinuation of antiplatelet therapy. VLST is concerning 
      since the underlying pathophysiology is unknown, and the best preventive 
      treatments and duration of antiplatelet medication after stent implantation are 
      unknown.
CI  - Copyright: (c) 2022 Journal of Family Medicine and Primary Care.
FAU - Kumar, Tapan
AU  - Kumar T
AD  - Department of Cardiology, Tata Main Hospital, Jamshedpur, Jharkhand, India.
FAU - Shah, Mandar M
AU  - Shah MM
AD  - Department of Cardiology, Tata Main Hospital, Jamshedpur, Jharkhand, India.
FAU - Prajapati, Aparna
AU  - Prajapati A
AD  - Department of Cardiology, Tata Main Hospital, Jamshedpur, Jharkhand, India.
FAU - Pathak, Saurabh
AU  - Pathak S
AD  - Department of Nephrology, Tata Main Hospital, Jamshedpur, Jharkhand, India.
LA  - eng
PT  - Case Reports
DEP - 20220318
PL  - India
TA  - J Family Med Prim Care
JT  - Journal of family medicine and primary care
JID - 101610082
PMC - PMC9067209
OTO - NOTNLM
OT  - Coronary artery disease
OT  - drug-eluting stents
OT  - neoatherosclerosis
OT  - neointima
OT  - paclitaxel eluting stent
OT  - very late stent thrombosis
COIS- There are no conflicts of interest
EDAT- 2022/05/07 06:00
MHDA- 2022/05/07 06:01
PMCR- 2022/04/01
CRDT- 2022/05/06 05:44
PHST- 2021/07/30 00:00 [received]
PHST- 2021/08/01 00:00 [revised]
PHST- 2021/11/24 00:00 [accepted]
PHST- 2022/05/06 05:44 [entrez]
PHST- 2022/05/07 06:00 [pubmed]
PHST- 2022/05/07 06:01 [medline]
PHST- 2022/04/01 00:00 [pmc-release]
AID - JFMPC-11-1545 [pii]
AID - 10.4103/jfmpc.jfmpc_1533_21 [doi]
PST - ppublish
SO  - J Family Med Prim Care. 2022 Apr;11(4):1545-1548. doi: 
      10.4103/jfmpc.jfmpc_1533_21. Epub 2022 Mar 18.