PMID- 35524381
OWN - NLM
STAT- MEDLINE
DCOM- 20220510
LR  - 20220510
IS  - 1735-5249 (Electronic)
IS  - 1735-1502 (Linking)
VI  - 21
IP  - 1
DP  - 2022 Feb 6
TI  - Identification of the Most Common Allergens of Acer velutinum Pollen.
PG  - 81-85
LID - 10.18502/ijaai.v21i1.8620 [doi]
AB  - Pollens have been identified as potent inducers of allergic diseases worldwide. 
      Acer velutinum (Persian maple) tree is an important source of allergic pollens in 
      Iran. This study aimed to identify the immunoglobulin E (IgE)-reactive components 
      of A. velutinum pollen extract in patients with maple allergy. We aimed to 
      evaluate its allergenic components; using IgE in the serum of patients with maple 
      allergy. Twenty-two patients with a clinical history of reaction and a positive 
      skin-prick test to maple pollen extract were included in this study. 
      Identification of IgE-binding proteins in A. velutinum pollen extract was 
      performed by immunoblotting using sera from sensitive patients. A protein band 
      with a molecular weight of around 70 kDa was the most IgE-reactive allergen in A. 
      velutinum pollen extract detected by this method. Identification of a protein 
      with a molecular weight of about 70kDa, as the most reactive allergen of A. 
      velutinum pollen extract, can be considered as a potential allergen for designing 
      diagnostic kits or as a target for immunotherapy of allergic patients with maple 
      allergy.
FAU - Sepahi, Najmeh
AU  - Sepahi N
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. 
      n_sepahi@yahoo.com.
FAU - Alyasin, Soheila
AU  - Alyasin S
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AND 
      Department of Allergy and Clinical Immunology, Namazi Hospital, Shiraz, Iran. 
      alyasins@sums.ac.ir.
FAU - Kanannejad, Zahra
AU  - Kanannejad Z
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. 
      zkanannejad@gmail.com.
FAU - Esmaeilzadeh, Hossein
AU  - Esmaeilzadeh H
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AND 
      Department of Allergy and Clinical Immunology, Namazi Hospital, Shiraz, Iran. 
      farjadsh@sums.ac.ir.
FAU - Mohammadalizadeh Shirazi, Farzaneh
AU  - Mohammadalizadeh Shirazi F
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. 
      alizadef@gmail.com.
FAU - Babaei, Maryam
AU  - Babaei M
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. 
      immunolab@sums.ac.ir.
FAU - Farjadian, Shirin
AU  - Farjadian S
AD  - Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AND 
      Department of Immunology, Shiraz University of Medical Sciences, Shiraz, Iran. 
      farjadsh@sums.ac.ir.
LA  - eng
PT  - Journal Article
DEP - 20220206
PL  - Iran
TA  - Iran J Allergy Asthma Immunol
JT  - Iranian journal of allergy, asthma, and immunology
JID - 101146178
RN  - 0 (Allergens)
RN  - 0 (Plant Extracts)
RN  - 0 (Plant Proteins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - *Acer
MH  - Allergens/analysis
MH  - Cross Reactions
MH  - Humans
MH  - *Hypersensitivity
MH  - Immunoglobulin E
MH  - Plant Extracts/chemistry/therapeutic use
MH  - Plant Proteins
MH  - Pollen
MH  - Skin Tests
OTO - NOTNLM
OT  - Hypersensitivity
OT  - Immunoglobulin E
OT  - Pollen
EDAT- 2022/05/08 06:00
MHDA- 2022/05/11 06:00
CRDT- 2022/05/07 01:00
PHST- 2021/06/27 00:00 [received]
PHST- 2021/10/10 00:00 [accepted]
PHST- 2022/05/07 01:00 [entrez]
PHST- 2022/05/08 06:00 [pubmed]
PHST- 2022/05/11 06:00 [medline]
AID - 10.18502/ijaai.v21i1.8620 [doi]
PST - epublish
SO  - Iran J Allergy Asthma Immunol. 2022 Feb 6;21(1):81-85. doi: 
      10.18502/ijaai.v21i1.8620.