PMID- 35529004
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230502
IS  - 0970-9134 (Print)
IS  - 0973-7723 (Electronic)
IS  - 0970-9134 (Linking)
VI  - 38
IP  - 3
DP  - 2022 May
TI  - Does tuberculosis affect surgical outcomes following pericardiectomy for chronic 
      constrictive pericarditis? Twelve years' experience from a tertiary care center 
      in India.
PG  - 241-250
LID - 10.1007/s12055-021-01313-y [doi]
AB  - INTRODUCTION AND PURPOSE: Tuberculosis (TB) is the commonest cause of chronic 
      constrictive pericarditis (CCP) in India, unlike in the western countries. 
      Pericardiectomy is the treatment of choice for CCP. Surgery in TB CCP is 
      considerably more difficult than it is for other etiologies. The role of TB as an 
      independent predictor for adverse surgical outcomes had not been properly 
      evaluated in the Indian scenario. Hence, the aim of this study was to 
      retrospectively analyze our results of surgery for CCP and the pre-operative 
      factors that influenced post-operative outcomes. METHODS: The data of all adult 
      patients who underwent pericardiectomy for CCP, between the years 2009 and 2020, 
      maintained in a live database in our institute, were retrieved and analyzed. 
      RESULTS: There were 124 patients in the study. The average age was 32 years. The 
      male to female ratio was 3:1. TB was the commonest cause of CCP, identified in 64 
      (51.6%) patients. Complete anterior pericardiectomy (CAP) was possible in 122 
      (98.3%) patients. All the patients had significant drop in their central venous 
      pressure (CVP) (10.25 +/- 3.47 mmHg) after surgery. The operative time (p = 0.008), 
      intra-operative blood loss (p = 0.02), intensive care unit (ICU) stay (p = 0.03), 
      and hospital stay (p = 0.028) were significantly higher in the TB group. Apart 
      from TB, the other pre-operative variables that predicted adverse outcomes were 
      male sex, presence of pleural effusion or ascites, and advanced New York Heart 
      Association (NYHA) class. There were 7 (5.6%) post-operative complications and 3 
      (2.4%) in-hospital deaths. CONCLUSION: The high incidence of TB CCP makes a 
      pericardiectomy in developing countries technically more challenging resulting in 
      increased operative time, more blood loss, and prolonged ICU and hospital stay, 
      but did not affect in-hospital mortality or morbidity.
CI  - (c) Indian Association of Cardiovascular-Thoracic Surgeons 2022.
FAU - Benjamin, Santhosh Regini
AU  - Benjamin SR
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Mohammad, Aamir
AU  - Mohammad A
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Shankar, Ravi
AU  - Shankar R
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Kuruvilla, Korah Thomas
AU  - Kuruvilla KT
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Philip, Madhu Andrew
AU  - Philip MA
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Thankachen, Roy
AU  - Thankachen R
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Gnanamuthu, Birla Roy
AU  - Gnanamuthu BR
AUID- ORCID: 0000-0003-4821-8802
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
FAU - Kesavan, Premprasath
AU  - Kesavan P
AD  - The Department of Cardiothoracic Surgery, The Christian Medical College, Tamil 
      Nadu, Vellore, 632004 India. GRID: grid.11586.3b. ISNI: 0000 0004 1767 8969
LA  - eng
PT  - Journal Article
DEP - 20220205
PL  - India
TA  - Indian J Thorac Cardiovasc Surg
JT  - Indian journal of thoracic and cardiovascular surgery
JID - 8700105
PMC - PMC9023633
OTO - NOTNLM
OT  - Congestive heart failure
OT  - Constrictive pericarditis
OT  - Pericardiectomy
OT  - Tuberculosis
COIS- Conflict of interestThere was no conflict of interest in this study.
EDAT- 2022/05/10 06:00
MHDA- 2022/05/10 06:01
PMCR- 2023/05/01
CRDT- 2022/05/09 04:04
PHST- 2021/07/31 00:00 [received]
PHST- 2021/12/04 00:00 [revised]
PHST- 2021/12/07 00:00 [accepted]
PHST- 2022/05/09 04:04 [entrez]
PHST- 2022/05/10 06:00 [pubmed]
PHST- 2022/05/10 06:01 [medline]
PHST- 2023/05/01 00:00 [pmc-release]
AID - 1313 [pii]
AID - 10.1007/s12055-021-01313-y [doi]
PST - ppublish
SO  - Indian J Thorac Cardiovasc Surg. 2022 May;38(3):241-250. doi: 
      10.1007/s12055-021-01313-y. Epub 2022 Feb 5.