PMID- 35532590
OWN - NLM
STAT- MEDLINE
DCOM- 20220511
LR  - 20220716
IS  - 0971-5916 (Print)
IS  - 0975-9174 (Electronic)
IS  - 0971-5916 (Linking)
VI  - 154
IP  - 5
DP  - 2021 May
TI  - Retrospective study of the effect of sarcopaenia on post-operative outcomes in 
      patients undergoing thoracic surgery.
PG  - 723-731
LID - 10.4103/ijmr.IJMR_909_19 [doi]
AB  - BACKGROUND & OBJECTIVES: Sarcopaenia refers to the pathological loss of muscle 
      mass that may be observed in malnutrition, immobility, chronic disease, 
      particularly chronic obstructive pulmonary disease and malignancies. A 
      relationship has been identified between sarcopaenia and thoracic surgery. The 
      aim of the present study was to investigate the relationship between density and 
      area of the psoas major muscle (PSM), the pectoralis major and minor muscles 
      (PEC) and the post-operative morbidity, mortality and survival of patients 
      undergoing anatomic lung resection. METHODS: A retrospective review of the 
      medical record data of the patients who underwent lung resection was conducted in 
      between 2009 and 2018. The study included patients who underwent upper abdominal 
      computed tomography (CT) for the measurement of PSM and thoracic CT for PEC. The 
      demographic data, laboratory test results, radiological findings and the survival 
      data of the patients were recorded. RESULTS: Evaluation was made of 161 patients 
      with available CT data. With the exception of mean PEC density, the PEC 
      parameters (P=0.013-0.026), and PSM density (P=0.015) were significantly lower in 
      the non-survivors than in the survivors. In general, the mean measurements of the 
      PSM and PEC were seen to affect mortality (P=0.001-0.024). INTERPRETATION & 
      CONCLUSIONS: The mean area and density measurements in the PSM, and particularly 
      in the PEC, were determined to be significantly higher in patients who survived 
      after lung cancer surgery, suggesting that sarcopaenia could be a useful 
      predictor of post-operative mortality risk and survival.
FAU - Karapinar, Kemal
AU  - Karapinar K
AD  - Department of Thoracic Surgery, Yedikule Training & Research Hospital for Chest 
      Diseases & Surgery, Health Science University, Istanbul, Turkey.
FAU - Toptas, Mehmet
AU  - Toptas M
AD  - Department of Anesthesiology, Yedikule Training & Research Hospital for Chest 
      Diseases & Surgery, Health Science University, Istanbul, Turkey.
FAU - Yurt, Sibel
AU  - Yurt S
AD  - Department of Chest Diseases, Yedikule Training & Research Hospital for Chest 
      Diseases & Surgery, Health Science University, Istanbul, Turkey.
FAU - Tuna, Lale
AU  - Tuna L
AD  - Department of Radiology, Yedikule Training & Research Hospital for Chest Diseases 
      & Surgery, Health Science University, Istanbul, Turkey.
FAU - Akkoc, Ibrahim
AU  - Akkoc I
AD  - Department of Anesthesiology, Haseki Training & Research Hospital, Health Science 
      University, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Med Res
JT  - The Indian journal of medical research
JID - 0374701
SB  - IM
MH  - Humans
MH  - Psoas Muscles
MH  - Retrospective Studies
MH  - *Sarcopenia
MH  - *Thoracic Surgery
MH  - Tomography, X-Ray Computed
PMC - PMC9210537
OTO - NOTNLM
OT  - Lung cancer
OT  - morbidity
OT  - mortality
OT  - sarcopaenia
OT  - thoracic surgery
COIS- Conflicts of Interest: None.
EDAT- 2022/05/10 06:00
MHDA- 2022/05/12 06:00
PMCR- 2021/11/01
CRDT- 2022/05/09 10:58
PHST- 2022/05/09 10:58 [entrez]
PHST- 2022/05/10 06:00 [pubmed]
PHST- 2022/05/12 06:00 [medline]
PHST- 2021/11/01 00:00 [pmc-release]
AID - IndianJMedRes_2021_154_5_723_344559 [pii]
AID - IJMR-154-723 [pii]
AID - 10.4103/ijmr.IJMR_909_19 [doi]
PST - ppublish
SO  - Indian J Med Res. 2021 May;154(5):723-731. doi: 10.4103/ijmr.IJMR_909_19.