PMID- 35533424
OWN - NLM
STAT- MEDLINE
DCOM- 20220524
LR  - 20220524
IS  - 1873-376X (Electronic)
IS  - 1570-0232 (Linking)
VI  - 1200
DP  - 2022 Jun 1
TI  - Quantification of Glucose, fructose and 1,5-Anhydroglucitol in plasma of diabetic 
      patients by ultra performance liquid chromatography tandem mass spectrometry.
PG  - 123277
LID - S1570-0232(22)00181-7 [pii]
LID - 10.1016/j.jchromb.2022.123277 [doi]
AB  - Type 2 diabetes mellitus (T2DM), a worldwide disease that affects the quality of 
      human life and social development. Glucose, fructose and 1,5-anhydroglucitol are 
      closely related to diabetes mellitus. However, few methods have been reported to 
      achieve these three carbohydrates in the blood simultaneously. In this study, a 
      UPLC-MS/MS method allowing to quantify glucose, fructose, and 1,5-anhydroglucitol 
      simultaneously in human plasma was developed. The analysis was performed by 
      UPLC-MS/MS system with HILIC column. This new method provided satisfactory 
      results in terms of calibration curves with good linearity (R(2) > 0.99) over 3 
      order of magnitude range, precision (coefficient of variation of intra-day and 
      inter-day: 0.72-10.23% and 2.21-13.8%), accuracy (results of intra-day and 
      inter-day: 97-113%, 100-107%), matrix effects (87-109%), recovery (93-119%), 
      carry-over (0.004-0.014%), as well as stability (0.04-6.9%) within the acceptance 
      criteria. The reproducible, precise and accurate method with suitable dynamic 
      ranges was successfully applied to the analysis of glucose, fructose and 
      1,5-anhydroglucitol in T2DM under different pathophysiological conditions.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Li, Mengna
AU  - Li M
AD  - Department of Endocrinology, Shenzhen Second People's Hospital/the First 
      Affiliated Hospital of Shenzhen University, Graduate School of Guangzhou Medical 
      University, Shenzhen 518035, China; The Central Laboratory, Shenzhen Second 
      People's Hospital/the First Affiliated Hospital of Shenzhen University Health 
      Science Center, Graduate School of Guangzhou Medical University, Shenzhen 518035, 
      China.
FAU - Yan, Dewen
AU  - Yan D
AD  - Department of Endocrinology, Shenzhen Second People's Hospital/the First 
      Affiliated Hospital of Shenzhen University, Graduate School of Guangzhou Medical 
      University, Shenzhen 518035, China.
FAU - Hao, Mingyu
AU  - Hao M
AD  - Department of Endocrinology, Shenzhen Second People's Hospital/the First 
      Affiliated Hospital of Shenzhen University, Graduate School of Guangzhou Medical 
      University, Shenzhen 518035, China.
FAU - Huang, Xiaohong
AU  - Huang X
AD  - Department of Endocrinology, Shenzhen Second People's Hospital/the First 
      Affiliated Hospital of Shenzhen University, Graduate School of Guangzhou Medical 
      University, Shenzhen 518035, China.
FAU - Xu, Yun
AU  - Xu Y
AD  - The Central Laboratory, Shenzhen Second People's Hospital/the First Affiliated 
      Hospital of Shenzhen University Health Science Center, Graduate School of 
      Guangzhou Medical University, Shenzhen 518035, China.
FAU - Li, Weifeng
AU  - Li W
AD  - The Central Laboratory, Shenzhen Second People's Hospital/the First Affiliated 
      Hospital of Shenzhen University Health Science Center, Graduate School of 
      Guangzhou Medical University, Shenzhen 518035, China. Electronic address: 
      weifengli@email.szu.edu.cn.
FAU - Liu, Wenlan
AU  - Liu W
AD  - The Central Laboratory, Shenzhen Second People's Hospital/the First Affiliated 
      Hospital of Shenzhen University Health Science Center, Graduate School of 
      Guangzhou Medical University, Shenzhen 518035, China. Electronic address: 
      wlliu@szu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20220504
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 30237-26-4 (Fructose)
RN  - 54BB3B7XMZ (1,5-anhydroglucitol)
RN  - 9G2MP84A8W (Deoxyglucose)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Chromatography, High Pressure Liquid/methods
MH  - Chromatography, Liquid
MH  - Deoxyglucose
MH  - *Diabetes Mellitus, Type 2
MH  - Fructose
MH  - Glucose
MH  - Humans
MH  - Reproducibility of Results
MH  - *Tandem Mass Spectrometry/methods
OTO - NOTNLM
OT  - 1,5-anhydroglucitol
OT  - Diabetes mellitus
OT  - Fructose
OT  - Glucose
OT  - UPLC-MS/MS
EDAT- 2022/05/10 06:00
MHDA- 2022/05/25 06:00
CRDT- 2022/05/09 18:14
PHST- 2022/01/19 00:00 [received]
PHST- 2022/04/11 00:00 [revised]
PHST- 2022/05/01 00:00 [accepted]
PHST- 2022/05/10 06:00 [pubmed]
PHST- 2022/05/25 06:00 [medline]
PHST- 2022/05/09 18:14 [entrez]
AID - S1570-0232(22)00181-7 [pii]
AID - 10.1016/j.jchromb.2022.123277 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jun 1;1200:123277. doi: 
      10.1016/j.jchromb.2022.123277. Epub 2022 May 4.