PMID- 35538613
OWN - NLM
STAT- MEDLINE
DCOM- 20230105
LR  - 20230111
IS  - 2472-5625 (Electronic)
IS  - 2472-5625 (Linking)
VI  - 7
IP  - 1
DP  - 2023 Jan 3
TI  - Mimic or coincidentally? TAFRO syndrome and systemic lupus erythematosus: A 
      case-based review.
PG  - 271-275
LID - 10.1093/mrcr/rxac045 [doi]
AB  - Castleman's disease (CD) is a rare, systemic disease with histopathological 
      features of angiofollicular lymph node hyperplasia. In the literature, there are 
      case-level reports that mimic or coexist with systemic lupus erythematosus (SLE) 
      clinically and in the laboratory. Is this condition two separate diseases or is 
      it an imitation of each other? A 73-year-old female patient was admitted to our 
      clinic with arthritis, lymphadenopathy, fever, weight loss, and malar rash. He 
      had a history of idiopathic thrombocytopenic purpura and thrombosis in the right 
      leg tibialis posterior and dorsalis pedis arteries. Excisional lymphadenopathy 
      biopsy indicated a diagnosis of hyaline-vascular-type CD. She had anti-nuclear 
      antibody >1/80 homogeneous pattern, anti-double stranded DNA (anti-dsDNA), 
      Anti-Smith (Sm) antibody positivity, hypocomplementemia (C3 and C4), pleural 
      effusion, and pericardial effusion. For this reason, the classification criteria 
      of the European League Against Rheumatism/American College of Rheumatology were 
      studied. Clinical findings, idiopathic thrombocytopenic purpura history, antibody 
      positivity, malar rash, and arthritis led us to the diagnosis of SLE. She was 
      treated with 1 mg/kg/day prednisolone and hydroxychloroquine 200 mg 2 x 1. 
      Azathioprine 2.5 mg/kg daily was added to the patient whose complaints did not 
      improve. In the follow-ups, she completely recovered clinically and laboratory. 
      SLE and CD are systemic diseases that overlap in many ways. The literature review 
      shows that these two diseases may mimic each other or may coexist. This situation 
      may be a reflection of a pathophysiological process that has not yet been 
      clarified. This confusing process also affects the treatment decision. This 
      confusing process also affects the treatment decision.
CI  - (c) Japan College of Rheumatology 2022. Published by Oxford University Press. All 
      rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
FAU - Okyar, Burak
AU  - Okyar B
AUID- ORCID: 0000-0002-9028-9930
AD  - Division of Rheumatology, Department of Internal Medicine, Kahramanmaras Sutcu 
      Imam University Faculty of Medicine, Onikisubat/Kahramanmaras, Turkey.
FAU - Torun, Bekir
AU  - Torun B
AD  - Division of Rheumatology, Department of Internal Medicine, Kahramanmaras Sutcu 
      Imam University Faculty of Medicine, Onikisubat/Kahramanmaras, Turkey.
FAU - Oktem, Esen Saba
AU  - Oktem ES
AD  - Division of Rheumatology, Department of Internal Medicine, Kahramanmaras Sutcu 
      Imam University Faculty of Medicine, Onikisubat/Kahramanmaras, Turkey.
FAU - Bahar, Abdulkadir Yasir
AU  - Bahar AY
AD  - Department of Pathology, Kahramanmaras Sutcu Imam University Faculty of Medicine, 
      Onikisubat/Kahramanmaras, Turkey.
FAU - Yildiz, Fatih
AU  - Yildiz F
AD  - Division of Rheumatology, Department of Internal Medicine, Kahramanmaras Sutcu 
      Imam University Faculty of Medicine, Onikisubat/Kahramanmaras, Turkey.
FAU - Cetin, Gozde Yildirim
AU  - Cetin GY
AD  - Division of Rheumatology, Department of Internal Medicine, Kahramanmaras Sutcu 
      Imam University Faculty of Medicine, Onikisubat/Kahramanmaras, Turkey.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Mod Rheumatol Case Rep
JT  - Modern rheumatology case reports
JID - 101761026
RN  - 0 (Antibodies, Antinuclear)
RN  - Multi-centric Castleman's Disease
RN  - malar rash
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - Aged
MH  - *Castleman Disease/complications/diagnosis
MH  - *Purpura, Thrombocytopenic, Idiopathic/complications
MH  - *Lupus Erythematosus, Systemic/complications/diagnosis/drug therapy
MH  - Antibodies, Antinuclear
MH  - *Lymphadenopathy/complications
MH  - *Arthritis
OTO - NOTNLM
OT  - Castleman's disease
OT  - TAFRO syndrome
OT  - systemic lupus erythematosus
EDAT- 2022/05/12 06:00
MHDA- 2023/01/06 06:00
CRDT- 2022/05/11 00:23
PHST- 2022/03/25 00:00 [received]
PHST- 2022/04/20 00:00 [revised]
PHST- 2022/04/26 00:00 [accepted]
PHST- 2022/05/12 06:00 [pubmed]
PHST- 2023/01/06 06:00 [medline]
PHST- 2022/05/11 00:23 [entrez]
AID - 6583475 [pii]
AID - 10.1093/mrcr/rxac045 [doi]
PST - ppublish
SO  - Mod Rheumatol Case Rep. 2023 Jan 3;7(1):271-275. doi: 10.1093/mrcr/rxac045.