PMID- 35542496
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220615
IS  - 2046-2069 (Electronic)
IS  - 2046-2069 (Linking)
VI  - 8
IP  - 50
DP  - 2018 Aug 7
TI  - Expedient synthesis of eumelanin-inspired 5,6-dihydroxyindole-2-carboxylate ethyl 
      ester derivatives.
PG  - 28323-28328
LID - 10.1039/c8ra06148c [doi]
AB  - Dihydroxyindoles such as 5,6-dihydroxyindole-2-carboxylic acid (DHICA) are the 
      main monomer units of eumelanin, the black to brown pigment in humans, and have 
      emerging biological roles beyond melanin. Elaboration of commercially available 
      5,6-dimethoxy-2-carboxylate ethyl ester provides ready access to DHICA-inspired 
      small molecules, including 3-(hetero)aryl-indoles and 
      4,7-di-(hetero)aryl-indoles.
CI  - This journal is (c) The Royal Society of Chemistry.
FAU - Aebly, Andrew H
AU  - Aebly AH
AD  - Department of Chemistry and Biochemistry, Oberlin College 119 Woodland St. 
      Oberlin OH 44074 USA Jason.Belitsky@Oberlin.edu.
FAU - Levy, Jeffrey N
AU  - Levy JN
AD  - Department of Chemistry and Biochemistry, Oberlin College 119 Woodland St. 
      Oberlin OH 44074 USA Jason.Belitsky@Oberlin.edu.
FAU - Steger, Benjamin J
AU  - Steger BJ
AD  - Department of Chemistry and Biochemistry, Oberlin College 119 Woodland St. 
      Oberlin OH 44074 USA Jason.Belitsky@Oberlin.edu.
FAU - Quirke, Jonathan C
AU  - Quirke JC
AD  - Department of Chemistry and Biochemistry, Oberlin College 119 Woodland St. 
      Oberlin OH 44074 USA Jason.Belitsky@Oberlin.edu.
FAU - Belitsky, Jason M
AU  - Belitsky JM
AUID- ORCID: 0000-0002-7998-3892
AD  - Department of Chemistry and Biochemistry, Oberlin College 119 Woodland St. 
      Oberlin OH 44074 USA Jason.Belitsky@Oberlin.edu.
LA  - eng
PT  - Journal Article
DEP - 20180807
PL  - England
TA  - RSC Adv
JT  - RSC advances
JID - 101581657
EIN - RSC Adv. 2019 Sep 3;9(48):27754. PMID: 35532451
PMC - PMC9083952
COIS- There are no conflicts of interest to declare.
EDAT- 2018/08/07 00:00
MHDA- 2018/08/07 00:01
PMCR- 2018/08/07
CRDT- 2022/05/11 04:09
PHST- 2018/07/20 00:00 [received]
PHST- 2019/09/03 00:00 [revised]
PHST- 2018/07/28 00:00 [accepted]
PHST- 2022/05/11 04:09 [entrez]
PHST- 2018/08/07 00:00 [pubmed]
PHST- 2018/08/07 00:01 [medline]
PHST- 2018/08/07 00:00 [pmc-release]
AID - c8ra06148c [pii]
AID - 10.1039/c8ra06148c [doi]
PST - epublish
SO  - RSC Adv. 2018 Aug 7;8(50):28323-28328. doi: 10.1039/c8ra06148c. eCollection 2018 
      Aug 7.