PMID- 35549801
OWN - NLM
STAT- MEDLINE
DCOM- 20230508
LR  - 20230513
IS  - 1464-5165 (Electronic)
IS  - 0963-8288 (Linking)
VI  - 45
IP  - 10
DP  - 2023 May
TI  - Minimal clinically important difference of the King's Parkinson's disease Pain 
      Scale.
PG  - 1680-1683
LID - 10.1080/09638288.2022.2074152 [doi]
AB  - OBJECTIVE: Pain is a common and debilitating symptom of Parkinson's disease (PD) 
      and has no specific treatment. King's Parkinson's disease Pain Scale (KPPS) is 
      the only specific scale for pain measurement in PD with established psychometric 
      properties. The minimal clinically important difference (MCID) of KPPS, an 
      important parameter for the design and interpretation of therapeutic 
      interventions, has not yet been measured. The aim of our study was to assess the 
      MCID of KPPS. METHODS: Two hundred and seven PD patients were evaluated by KPPS 
      before and after receiving the intervention. The Clinical Global Impression of 
      Improvement Scale was used as an anchor, and a Receiver Operating Characteristic 
      (ROC) curve was used to determine the optimal MCID cut-off point for KPPS. The 
      distribution-based approach applied one-third standard deviation (SD), 0.5 SD, 
      and one standard error of measurement (SEM) of the total score of KPPS to 
      determine the MCID. RESULTS: The MCID achieved from the ROC curve was 3 points 
      (sensitivity: 74.4%; specificity: 81.9%). For the distribution-based method, the 
      MCIDs corresponding to 0.3 SD, 0.5 SD, and one SEM were 5.65, 9.41, and 2.54 
      points, respectively. CONCLUSION: KPPS is a valid scale for measuring pain in PD 
      with demonstrable MCID. IMPLICATIONS FOR REHABILITATIONThe King's Parkinson's 
      disease Pain Scale (KPPS) is a valid scale for measuring pain in patients with 
      Parkinson's disease (PD) with demonstrable minimal clinically important 
      difference (MCID).The MCID obtained in the current study will assist clinicians 
      and researchers when interpreting KPPS change score to determine clinically 
      meaningful changes of pain in both PD progression and response to interventions.
FAU - Taghizadeh, Ghorban
AU  - Taghizadeh G
AUID- ORCID: 0000-0002-0145-9599
AD  - Department of Occupational Therapy, School of Rehabilitation Sciences, 
      Rehabilitation Research Center, Iran University of Medical Science, Tehran, Iran.
FAU - Fereshtehnejad, Seyed-Mohammad
AU  - Fereshtehnejad SM
AD  - Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and 
      Society (NVS), Karolinska Institutet, Stockholm, Sweden.
AD  - Division of Neurology, Faculty of Medicine, University of Ottawa, Ottawa, ON, 
      Canada.
FAU - Goudarzi, Sepideh
AU  - Goudarzi S
AUID- ORCID: 0000-0001-8545-8560
AD  - Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University 
      of Medical Science, Tehran, Iran.
FAU - Jamali, Shamsi
AU  - Jamali S
AD  - Department of Occupational Therapy, School of Rehabilitation Sciences, 
      Rehabilitation Research Center, Iran University of Medical Science, Tehran, Iran.
FAU - Mehdizadeh, Maryam
AU  - Mehdizadeh M
AUID- ORCID: 0000-0003-2977-3421
AD  - Department of Neurosciences, Faculty of Advanced Technologies in Medicine, Iran 
      University of Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
DEP - 20220512
PL  - England
TA  - Disabil Rehabil
JT  - Disability and rehabilitation
JID - 9207179
SB  - IM
MH  - Humans
MH  - Pain Measurement
MH  - *Minimal Clinically Important Difference
MH  - *Parkinson Disease/complications/diagnosis
MH  - Psychometrics
MH  - Pain/diagnosis/etiology
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Anchor-based
OT  - Distribution-based
OT  - Minimal clinically important difference
OT  - Pain
OT  - Parkinson's disease
EDAT- 2022/05/14 06:00
MHDA- 2023/05/08 06:41
CRDT- 2022/05/13 12:08
PHST- 2023/05/08 06:41 [medline]
PHST- 2022/05/14 06:00 [pubmed]
PHST- 2022/05/13 12:08 [entrez]
AID - 10.1080/09638288.2022.2074152 [doi]
PST - ppublish
SO  - Disabil Rehabil. 2023 May;45(10):1680-1683. doi: 10.1080/09638288.2022.2074152. 
      Epub 2022 May 12.