PMID- 35558051 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220519 IS - 2046-2069 (Electronic) IS - 2046-2069 (Linking) VI - 8 IP - 69 DP - 2018 Nov 23 TI - Magnetic solid-phase extraction using a mixture of two types of nanoparticles followed by gas chromatography-mass spectrometry for the determination of six phthalic acid esters in various water samples. PG - 39641-39649 LID - 10.1039/c8ra08643e [doi] AB - Two types of magnetic microspheres (Fe(3)O(4)@MIL-100 and Fe(3)O(4)@SiO(2)@polythiophene) were prepared and characterized as mixed sorbents for magnetic solid-phase extraction (MSPE) of six phthalic acid esters (PAEs), including dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DBP), benzyl butyl phthalate (BBP), di-2-ethylhexyl phthalate (DEHP), and di-n-octyl phthalate (DnOP) from water samples prior to gas chromatography-mass spectrometry (GC-MS) analysis. The synthetic magnetic nanocomposites exhibited good repeatability and chemical stability, and improved extraction efficiency for the tested PAEs. The mixture of the two types of nanoparticles substantially improved the extraction efficiency of both DMP and DEP. The key parameters affecting the extraction efficiency, such as the type and the amount of sorbent, eluent (desorption solvent), adsorption and desorption time, pH of sample solution, and sample volume, were investigated and optimized, respectively. Under optimized conditions, the developed method showed satisfactory linearity in the range of 5-5000 mug L(-1) with coefficients of determination (R (2)) > 0.9935. The method detection limits (MDLs) and limits of quantitation (LOQs) were between 0.35-0.91 mug L(-1) and 1.1-2.9 mug L(-1), respectively. At three fortification levels (1.0, 10.0, and 50.0 mug L(-1)), the mean recoveries ranged from 76.9-109.1% with favorable relative standard deviations (RSDs) < 9%. The feasibility of the method was evaluated by analysis of water samples from various sources (tap, drinking, and mineral water). The results show that the developed method is suitable for determination of trace level PAEs in water samples. CI - This journal is (c) The Royal Society of Chemistry. FAU - Li, Hui AU - Li H AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Cao, Zhen AU - Cao Z AUID- ORCID: 0000-0003-1259-6107 AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Cao, Xiaolin AU - Cao X AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Jiang, Zejun AU - Jiang Z AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Abd El-Aty, A M AU - Abd El-Aty AM AD - Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University 12211 Giza Egypt. AD - Department of Medical Pharmacology, Medical Faculty, Ataturk University Erzurum 25240 Republic of Turkey. FAU - Qi, Yan AU - Qi Y AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Shao, Hua AU - Shao H AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Jin, Fen AU - Jin F AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Zheng, Lufei AU - Zheng L AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. FAU - Wang, Jing AU - Wang J AD - Institute of Quality Standard and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-product Quality and Safety, Ministry of Agriculture Beijing 100081 P. R. China caozhen01@caas.cn +86-10-82106568 +86-010-82106513. LA - eng PT - Journal Article DEP - 20181127 PL - England TA - RSC Adv JT - RSC advances JID - 101581657 PMC - PMC9090721 COIS- The authors have declared no conflicts of interest. EDAT- 2018/11/27 00:00 MHDA- 2018/11/27 00:01 PMCR- 2018/11/27 CRDT- 2022/05/13 18:10 PHST- 2018/10/18 00:00 [received] PHST- 2018/11/21 00:00 [accepted] PHST- 2022/05/13 18:10 [entrez] PHST- 2018/11/27 00:00 [pubmed] PHST- 2018/11/27 00:01 [medline] PHST- 2018/11/27 00:00 [pmc-release] AID - c8ra08643e [pii] AID - 10.1039/c8ra08643e [doi] PST - epublish SO - RSC Adv. 2018 Nov 27;8(69):39641-39649. doi: 10.1039/c8ra08643e. eCollection 2018 Nov 23.