PMID- 35566984
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 14
IP  - 9
DP  - 2022 Apr 29
TI  - Eu(3+)- and Tb(3+)-Based Coordination Complexes of 
      Poly(N-Isopropyl,N-methylacrylamide-stat-N,N-dimethylacrylamide) Copolymer: 
      Synthesis, Characterization and Property.
LID - 10.3390/polym14091815 [doi]
LID - 1815
AB  - This contribution reports the syntheses, structural analyses and properties of 
      europium (Eu(3+))- and terbium (Tb(3+))-based coordination complexes of 
      poly(N-isopropyl,N-methylacrylamide-stat-N,N-dimethylacrylamide) 
      (poly(iPMAm-stat-DMAm)) copolymer, named as poly-Eu(III) and poly-Tb(III), 
      respectively. In greater detail, poly(iPMAm(85)-stat-DMAm(15)) is first prepared 
      by random copolymerization of N-isopropyl,N-methylacrylamide (iPMAm) and 
      N,N-dimethylacrylamide (DMAm) via group transfer polymerization (GTP). Next, 
      poly(iPMAm(85)-stat-DMAm(15)) is used as the polymer matrix for chelating with 
      Eu(3+) and Tb(3+) cations at its side amide groups, to produce poly-Eu(III) and 
      poly-Tb(III). Their structural characterizations by FT-IR spectroscopy and XPS 
      confirm the formation of polymeric complexes. The study on their fluorescence 
      emission characteristics and luminescence lifetime demonstrates that Poly-Eu(III) 
      shows four strong emission peaks at 578, 593, 622, and 651 nm, which are 
      responsible for the electron transitions from the excited (5)D(0) state to the 
      multiplet (7)F(J) (J = 0, 1, 2, 3) states, respectively, and poly-Tb(III) also 
      displays four emission peaks at 489, 545, 588, and 654 nm, mainly due to the 
      electron transitions of (5)D(4) --> (7)F(i) (i = 6, 5, 4, 3). The luminescence 
      lifetimes of poly-Eu(III) (tau(poly-Eu(III))) and poly-Tb(III) (tau(poly-Tb(III))) 
      are determined to be 4.57 and 7.50 ms, respectively. In addition, in aqueous 
      solutions, poly-Eu(III) and poly-Tb(III) are found to exhibit thermoresponsivity, 
      with their cloud temperatures (T(c)s) locating around 36.4 and 36.8  degrees C, 
      respectively. Finally, the cytotoxicity study on the human colon carcinoma cells 
      LoVo and DLD1 suggests that the luminescent Eu(3+) and Tb(3+) in the chelated 
      state with poly(iPMAm-stat-DMAm) show much better biocompatibility and lower 
      toxicity than their inorganic salts.
FAU - Li, Jian
AU  - Li J
AUID- ORCID: 0000-0003-1978-9438
AD  - Institute for Advanced Study, Shenzhen University, Shenzhen 518060, China.
AD  - College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 
      518060, China.
FAU - Cui, Guihua
AU  - Cui G
AD  - Department of Chemistry, Jilin Medical University, Jilin 132013, China.
FAU - Bi, Siyuan
AU  - Bi S
AUID- ORCID: 0000-0002-5597-6751
AD  - Shenzhen Huizhi Technology Co., Ltd., Shenzhen 518102, China.
FAU - Cui, Xu
AU  - Cui X
AD  - School of Materials Science and Engineering, Changchun University of Science and 
      Technology, Changchun 130022, China.
FAU - Li, Yanhui
AU  - Li Y
AD  - School of Materials Science and Engineering, Changchun University of Science and 
      Technology, Changchun 130022, China.
FAU - Duan, Qian
AU  - Duan Q
AD  - School of Materials Science and Engineering, Changchun University of Science and 
      Technology, Changchun 130022, China.
FAU - Kakuchi, Toyoji
AU  - Kakuchi T
AUID- ORCID: 0000-0001-9668-1442
AD  - School of Materials Science and Engineering, Changchun University of Science and 
      Technology, Changchun 130022, China.
AD  - Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, 
      Sapporo 060-8628, Japan.
FAU - Chen, Yougen
AU  - Chen Y
AD  - Institute for Advanced Study, Shenzhen University, Shenzhen 518060, China.
LA  - eng
GR  - No. 000215/Natural Science Foundation of Shenzhen University/
GR  - No. JCYJ20190808154011907/Shenzhen Science and Technology Research Grant/
GR  - No. 2017GC010440/Pearl River Talents Plan of Guangdong Province/
PT  - Journal Article
DEP - 20220429
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC9100629
OTO - NOTNLM
OT  - cell viability
OT  - fluorescent property
OT  - group transfer polymerization
OT  - rare earth complexes
OT  - thermoresponsive
COIS- The authors declare no conflict of interest.
EDAT- 2022/05/15 06:00
MHDA- 2022/05/15 06:01
PMCR- 2022/04/29
CRDT- 2022/05/14 01:28
PHST- 2022/04/12 00:00 [received]
PHST- 2022/04/25 00:00 [revised]
PHST- 2022/04/26 00:00 [accepted]
PHST- 2022/05/14 01:28 [entrez]
PHST- 2022/05/15 06:00 [pubmed]
PHST- 2022/05/15 06:01 [medline]
PHST- 2022/04/29 00:00 [pmc-release]
AID - polym14091815 [pii]
AID - polymers-14-01815 [pii]
AID - 10.3390/polym14091815 [doi]
PST - epublish
SO  - Polymers (Basel). 2022 Apr 29;14(9):1815. doi: 10.3390/polym14091815.