PMID- 35567359
OWN - NLM
STAT- MEDLINE
DCOM- 20220802
LR  - 20221207
IS  - 1522-2683 (Electronic)
IS  - 0173-0835 (Linking)
VI  - 43
IP  - 15
DP  - 2022 Aug
TI  - Determination of parabens in wastewater samples via robot-assisted dynamic 
      single-drop microextraction and liquid chromatography-tandem mass spectrometry.
PG  - 1567-1576
LID - 10.1002/elps.202100390 [doi]
AB  - Dynamic single-drop microextraction (SDME) was automatized employing an 
      Arduino-based lab-made Cartesian robot and implemented to determine parabens in 
      wastewater samples in combination with liquid chromatography-tandem mass 
      spectrometry. A dedicated Arduino sketch controls the auto-performance of all the 
      stages of the SDME process, including syringe filling, drop exposition, solvent 
      recycling, and extract collection. Univariate and multivariate experiments 
      investigated the main variables affecting the SDME performance, including 
      robot-dependent and additional operational parameters. Under selected conditions, 
      limit of detections were established at 0.3 microg/L for all the analytes, and the 
      method provided linear responses in the range between 0.6 and 10 microg/L, with 
      adequate reproducibility, measured as intraday relative standard deviations 
      (RSDs) between 5.54% and 17.94%, (n = 6), and inter-days RSDs between 8.97% and 
      16.49% (n = 9). The robot-assisted technique eased the control of dynamic SDME, 
      making the process more feasible, robust, and reliable so that the developed 
      setup demonstrated to be a competitive strategy for the automated extraction of 
      organic pollutants from water samples.
CI  - (c) 2022 Wiley-VCH GmbH.
FAU - Bocelli, Marcio David
AU  - Bocelli MD
AUID- ORCID: 0000-0001-5232-0899
AD  - Sao, Carlos Institute of Chemistry, University of Sao Paulo, Sao Carlos, Sao 
      Paulo, Brazil.
FAU - Vargas Medina, Deyber Arley
AU  - Vargas Medina DA
AUID- ORCID: 0000-0002-6528-8370
AD  - Sao, Carlos Institute of Chemistry, University of Sao Paulo, Sao Carlos, Sao 
      Paulo, Brazil.
FAU - Rodriguez, Julie Paulin Garcia
AU  - Rodriguez JPG
AD  - Sao, Carlos Institute of Chemistry, University of Sao Paulo, Sao Carlos, Sao 
      Paulo, Brazil.
FAU - Lancas, Fernando Mauro
AU  - Lancas FM
AUID- ORCID: 0000-0002-8711-5905
AD  - Sao, Carlos Institute of Chemistry, University of Sao Paulo, Sao Carlos, Sao 
      Paulo, Brazil.
FAU - Santos-Neto, Alvaro Jose
AU  - Santos-Neto AJ
AUID- ORCID: 0000-0003-1719-8458
AD  - Sao, Carlos Institute of Chemistry, University of Sao Paulo, Sao Carlos, Sao 
      Paulo, Brazil.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220526
PL  - Germany
TA  - Electrophoresis
JT  - Electrophoresis
JID - 8204476
RN  - 0 (Parabens)
RN  - 0 (Waste Water)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Chromatography, Liquid
MH  - *Liquid Phase Microextraction/methods
MH  - Parabens/analysis
MH  - Reproducibility of Results
MH  - *Robotics
MH  - Tandem Mass Spectrometry
MH  - Wastewater/analysis
MH  - *Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - automated sample preparation
OT  - liquid chromatography
OT  - liquid-phase microextraction
OT  - mass spectrometry
OT  - single-drop microextraction
EDAT- 2022/05/15 06:00
MHDA- 2022/08/03 06:00
CRDT- 2022/05/14 03:32
PHST- 2022/04/16 00:00 [revised]
PHST- 2021/12/24 00:00 [received]
PHST- 2022/04/25 00:00 [accepted]
PHST- 2022/05/15 06:00 [pubmed]
PHST- 2022/08/03 06:00 [medline]
PHST- 2022/05/14 03:32 [entrez]
AID - 10.1002/elps.202100390 [doi]
PST - ppublish
SO  - Electrophoresis. 2022 Aug;43(15):1567-1576. doi: 10.1002/elps.202100390. Epub 
      2022 May 26.