PMID- 35573566 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 14 IP - 4 DP - 2022 Apr TI - Intestinal Perforation as a Paradoxical Reaction to Tuberculosis. PG - e24077 LID - 10.7759/cureus.24077 [doi] LID - e24077 AB - Paradoxical reactions (PR) to tuberculosis (TB) treatments are characterized by an initial improvement of the clinical symptoms followed by a clinical or radiological deterioration of existing TB lesions or by the development of new lesions. PR in the gastrointestinal system is a rare phenomenon. Moreover, intestinal perforation is an uncommon but potentially fatal complication of intestinal TB. We report the case of a 29-year-old female who presented with fever and abdominal pain that was associated with watery diarrhea. She was diagnosed as a case of intestinal TB. During her stay, she developed intestinal perforation following the initiation of anti-TB treatment. She was eventually managed as a case of intestinal perforation as a PR to TB. CI - Copyright (c) 2022, Alebaji et al. FAU - Alebaji, Mohamad B AU - Alebaji MB AD - Pediatric Medicine, Tawam Hospital, Abu Dhabi, ARE. FAU - Omara, Abdelrahman I AU - Omara AI AD - Family Medicine, Ambulatory Health Services, Al Ain, ARE. LA - eng PT - Case Reports DEP - 20220412 PL - United States TA - Cureus JT - Cureus JID - 101596737 EIN - Cureus. 2022 Jun 10;14(6):c65. PMID: 35720787 PMC - PMC9098107 OTO - NOTNLM OT - arab countries OT - intestinal perforation OT - paradoxical reaction OT - tuberculosis OT - uae COIS- The authors have declared that no competing interests exist. EDAT- 2022/05/17 06:00 MHDA- 2022/05/17 06:01 PMCR- 2022/04/12 CRDT- 2022/05/16 04:29 PHST- 2022/04/12 00:00 [accepted] PHST- 2022/05/16 04:29 [entrez] PHST- 2022/05/17 06:00 [pubmed] PHST- 2022/05/17 06:01 [medline] PHST- 2022/04/12 00:00 [pmc-release] AID - 10.7759/cureus.24077 [doi] PST - epublish SO - Cureus. 2022 Apr 12;14(4):e24077. doi: 10.7759/cureus.24077. eCollection 2022 Apr.