PMID- 35578194
OWN - NLM
STAT- MEDLINE
DCOM- 20220519
LR  - 20220716
IS  - 1471-244X (Electronic)
IS  - 1471-244X (Linking)
VI  - 22
IP  - 1
DP  - 2022 May 16
TI  - Group treatment for complex dissociative disorders: a randomized clinical trial.
PG  - 338
LID - 10.1186/s12888-022-03970-8 [doi]
LID - 338
AB  - BACKGROUND: Patients with complex dissociative disorders (CDD) report high levels 
      of childhood- abuse experiences, clinical comorbidity, functional impairment, and 
      treatment utilization. Although a few naturalistic studies indicate that these 
      patients can benefit from psychotherapy, no randomized controlled trials have 
      been reported with this patient-group. The current study evaluates a structured 
      protocolled group treatment delivered in a naturalistic clinical setting to 
      patients with CDD, as an add-on to individual treatment. METHODS: Fifty nine 
      patients with CDD were randomized to 20 sessions of stabilizing group-treatment, 
      conjoint with individual therapy, or individual therapy alone, in a 
      delayed-treatment design. The treatment was based on the manual Coping with 
      Trauma-Related Dissociation. The primary outcome was Global Assessment of 
      Functioning (GAF), while secondary outcomes were PTSD and dissociative symptoms, 
      general psychopathology, and interpersonal difficulties. RESULTS: Mixed effect 
      models showed no condition x time interaction during the delayed treatment 
      period, indicating no immediate differences between conditions in the primary 
      outcome. Similar results were observed for secondary outcomes. Within-group 
      effects were non-significant in both conditions from baseline to end of 
      treatment, but significant improvements in psychosocial function, PTSD symptoms, 
      and general psychopathology were observed over a 6-months follow-up period. 
      CONCLUSION: In the first randomized controlled trial for the treatment of complex 
      dissociative disorders, stabilizing group treatment did not produce immediate 
      superior outcomes. Treatment was shown to be associated with improvements in 
      psychological functioning. TRIAL REGISTRATION: Clinical Trials ( NCT02450617 ).
CI  - (c) 2022. The Author(s).
FAU - Baekkelund, Harald
AU  - Baekkelund H
AD  - Research Institute, Modum Bad Psychiatric Hospital, Vikersund, Norway. 
      harald.bakkelund@nkvts.no.
AD  - Section for Implementation and Treatment Research, Norwegian Center for Violence 
      and Traumatic Stress Studies, Oslo, Norway. harald.bakkelund@nkvts.no.
AD  - Department of Psychology, Faculty of Social Sciences, University of Oslo, Oslo, 
      Norway. harald.bakkelund@nkvts.no.
FAU - Ulvenes, Pal
AU  - Ulvenes P
AD  - Research Institute, Modum Bad Psychiatric Hospital, Vikersund, Norway.
AD  - Department of Psychology, Faculty of Social Sciences, University of Oslo, Oslo, 
      Norway.
FAU - Boon-Langelaan, Suzette
AU  - Boon-Langelaan S
AD  - Private practice, Maarssen, The Netherlands.
FAU - Arnevik, Espen Ajo
AU  - Arnevik EA
AD  - Section for clinical addiction research, Oslo University Hospital, Oslo, Norway.
LA  - eng
SI  - ClinicalTrials.gov/NCT02450617
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20220516
PL  - England
TA  - BMC Psychiatry
JT  - BMC psychiatry
JID - 100968559
SB  - IM
MH  - Child
MH  - *Child Abuse
MH  - *Cognitive Behavioral Therapy/methods
MH  - Comorbidity
MH  - Dissociative Disorders/therapy
MH  - Humans
MH  - Psychotherapy/methods
MH  - *Stress Disorders, Post-Traumatic/psychology
MH  - Treatment Outcome
PMC - PMC9112598
OTO - NOTNLM
OT  - Dissociative disorders
OT  - Group psychotherapy
OT  - Psychological trauma
OT  - Psychotherapy outcome research
OT  - Randomized clinical trial
COIS- SB is the first author of the treatment manual of the study and receives royalty 
      from W. W. Norton & Company. She also received consultation fees for trainings in 
      the use of the manual and treatment of dissociative disorders. The other authors 
      have no conflicts of interest to declare.
EDAT- 2022/05/17 06:00
MHDA- 2022/05/20 06:00
PMCR- 2022/05/16
CRDT- 2022/05/16 23:45
PHST- 2021/08/31 00:00 [received]
PHST- 2022/04/21 00:00 [accepted]
PHST- 2022/05/16 23:45 [entrez]
PHST- 2022/05/17 06:00 [pubmed]
PHST- 2022/05/20 06:00 [medline]
PHST- 2022/05/16 00:00 [pmc-release]
AID - 10.1186/s12888-022-03970-8 [pii]
AID - 3970 [pii]
AID - 10.1186/s12888-022-03970-8 [doi]
PST - epublish
SO  - BMC Psychiatry. 2022 May 16;22(1):338. doi: 10.1186/s12888-022-03970-8.