PMID- 35581639
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2055-0928 (Electronic)
IS  - 2055-0928 (Linking)
VI  - 8
IP  - 1
DP  - 2022 May 17
TI  - Pomegranate juice intake enhances the effects of aerobic training on insulin 
      resistance and liver enzymes in type 2 diabetic men: a single-blind controlled 
      trial.
PG  - 48
LID - 10.1186/s40795-022-00538-3 [doi]
LID - 48
AB  - BACKGROUND: Lifestyle interventions are the first-line treatment for Type 2 
      diabetes mellitus (T2DM), highly prevalent in the community. This study aimed to 
      examine the 8-week separate and combined effects of aerobic training (AT) and 
      pomegranate juice intake (PJI) on insulin resistance and serum levels of liver 
      enzymes, liver enzymes, and insulin resistance in men with T2DM. METHODS: This 
      study evaluated the alterations of anthropometric indices, insulin resistance, 
      and liver enzymes in 40 middle-aged men (40-50) with T2DM. Participants were 
      randomly assigned into four groups: AT+PJI (n = 10); AT (n = 10); PJI (n = 10), 
      and control (C) (n = 10). The AT program consisted of 60-75% of maximum heart 
      rate (HR(max)), 40-60 min/day, and 3 days/wk. Participants in the PJI group 
      consumed 240 ml of pomegranate juice (sugar or additive-free) daily for 8 weeks. 
      RESULTS: AT+PJI, PJI, and AT groups decreased anthropometric indices, HOMA-IR, 
      and liver enzymes after 8 weeks. In contrast, the C group significantly increased 
      the mentioned variables after the intervention. The result showed that AT+PJI 
      significantly lowered liver enzymes, anthropometric indices, and HOMA-IR than AT 
      or PJI alone. Also, the results of this study showed no significant difference 
      between AT and PJI groups. However, in these groups, significant improvements in 
      these variables were observed compared to the control group. CONCLUSION: Due to 
      the effect of combined AT+PJI in improving T2DM risk factors, it could be 
      recommended for T2DM patients to prevent increased liver enzymes and insulin 
      resistance.
CI  - (c) 2022. The Author(s).
FAU - Nemati, Sasan
AU  - Nemati S
AUID- ORCID: 0000-0002-9273-476X
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, Razi University, 
      Kermanshah, Iran.
FAU - Tadibi, Vahid
AU  - Tadibi V
AUID- ORCID: 0000-0003-4560-5006
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, Razi University, 
      Kermanshah, Iran. Vtadibi@yahoo.com.
FAU - Hoseini, Rastegar
AU  - Hoseini R
AUID- ORCID: 0000-0001-8685-2471
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, Razi University, 
      Kermanshah, Iran.
LA  - eng
PT  - Journal Article
DEP - 20220517
PL  - England
TA  - BMC Nutr
JT  - BMC nutrition
JID - 101672434
PMC - PMC9112513
OTO - NOTNLM
OT  - Aerobic training
OT  - Complementary and alternative Medicine
OT  - Diabetes mellitus
OT  - Glycemic indexes
OT  - Integrative Medicine
OT  - Liver diseases
OT  - Pomegranate
COIS- The authors declare no conflict of interest.
EDAT- 2022/05/18 06:00
MHDA- 2022/05/18 06:01
PMCR- 2022/05/17
CRDT- 2022/05/17 23:41
PHST- 2022/01/29 00:00 [received]
PHST- 2022/04/27 00:00 [accepted]
PHST- 2022/05/17 23:41 [entrez]
PHST- 2022/05/18 06:00 [pubmed]
PHST- 2022/05/18 06:01 [medline]
PHST- 2022/05/17 00:00 [pmc-release]
AID - 10.1186/s40795-022-00538-3 [pii]
AID - 538 [pii]
AID - 10.1186/s40795-022-00538-3 [doi]
PST - epublish
SO  - BMC Nutr. 2022 May 17;8(1):48. doi: 10.1186/s40795-022-00538-3.