PMID- 35582050
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220519
IS  - 2307-8960 (Print)
IS  - 2307-8960 (Electronic)
IS  - 2307-8960 (Linking)
VI  - 10
IP  - 11
DP  - 2022 Apr 16
TI  - Reconstruction of complex chest wall defects: A case report.
PG  - 3505-3510
LID - 10.12998/wjcc.v10.i11.3505 [doi]
AB  - BACKGROUND: Chronic radiative chest wall ulcers are common in patients undergoing 
      radiation therapy. If not treated early, then symptoms such as erosion, bleeding 
      and infection will appear on the skin. In severe cases, ulcers invade the ribs 
      and pleura, presenting a mortality risk. Small ulcers can be repaired with 
      pedicle flaps. Because radioactive ulcers often invade the thorax, surgeons need 
      to remove large areas of skin and muscle, and sometimes ribs. Repairing large 
      chest wall defects are a challenge for surgeons. CASE SUMMARY: A 74-year-old 
      female patient was admitted to our department with chest wall skin ulceration 
      after radiation therapy for left breast cancer. The patient was diagnosed with 
      chronic radioactive ulceration. After multidisciplinary discussion, the authors 
      performed expansive resection of the chest wall ulcers and repaired large chest 
      wall defects using a deep inferior epigastric perforator (DIEP) flap combined 
      with a high-density polyethylene (HDPE) patch. The patient was followed-up 6 mo 
      after the operation. No pigmentation or edema was found in the flap. CONCLUSION: 
      DIEP flap plus HDPE patch is one of the better treatments for radiation-induced 
      chest wall ulcers.
CI  - (c)The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - Huang, Sheng-Chao
AU  - Huang SC
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Chen, Chun-Yan
AU  - Chen CY
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Qiu, Pu
AU  - Qiu P
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Yan, Ze-Ming
AU  - Yan ZM
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Chen, Wei-Zhang
AU  - Chen WZ
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Liang, Zhong-Zheng
AU  - Liang ZZ
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Luo, Kang-Wei
AU  - Luo KW
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Li, Jian-Wen
AU  - Li JW
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
FAU - Zhang, Yuan-Qi
AU  - Zhang YQ
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China. 
      31428319@qq.com.
FAU - Huang, Bao-Yi
AU  - Huang BY
AD  - Department of Vascular, Thyroid, and Breast Surgery, Affiliated Hospital of 
      Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China.
LA  - eng
PT  - Case Reports
PL  - United States
TA  - World J Clin Cases
JT  - World journal of clinical cases
JID - 101618806
PMC - PMC9048570
OTO - NOTNLM
OT  - Breast cancer
OT  - Case report
OT  - Chest wall
OT  - Chronic radiation-induced ulcer
OT  - Deep inferior epigastric perforator flap
OT  - High-density polyethylene patch
COIS- Conflict-of-interest statement: The authors declare no conflicts of interest.
EDAT- 2022/05/19 06:00
MHDA- 2022/05/19 06:01
PMCR- 2022/04/16
CRDT- 2022/05/18 02:05
PHST- 2021/12/15 00:00 [received]
PHST- 2022/02/03 00:00 [revised]
PHST- 2022/02/27 00:00 [accepted]
PHST- 2022/05/18 02:05 [entrez]
PHST- 2022/05/19 06:00 [pubmed]
PHST- 2022/05/19 06:01 [medline]
PHST- 2022/04/16 00:00 [pmc-release]
AID - 10.12998/wjcc.v10.i11.3505 [doi]
PST - ppublish
SO  - World J Clin Cases. 2022 Apr 16;10(11):3505-3510. doi: 
      10.12998/wjcc.v10.i11.3505.