PMID- 35582348
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220519
IS  - 1989-5488 (Print)
IS  - 1989-5488 (Electronic)
IS  - 1989-5488 (Linking)
VI  - 14
IP  - 5
DP  - 2022 May
TI  - Oral health aspects in sporadic and familial primary hyperparathyroidism.
PG  - e396-e403
LID - 10.4317/jced.59527 [doi]
AB  - BACKGROUND: Primary hyperparathyroidism (pHPT) is the third most common 
      endocrinopathy, affecting 1-3% of postmenopausal women, with a total incidence of 
      21.6 cases per 100,000 people in the adult population. This study aimed to 
      analyze the oral health and related aspects of individuals with pHPT. MATERIAL 
      AND METHODS: A cross-sectional observational study was carried out on 51 patients 
      diagnosed with pHPT associated with multiple endocrine neoplasia type 1 (MEN-1) 
      (G1) or sporadic pHPT (G2). The oral aspects investigated were periodontal 
      parameters, salivary flow, presence of dental caries, number of restored or 
      missing teeth, and presence of tori. The biochemical parameters were collected in 
      periods close to the dental evaluation. RESULTS: In G1, 29 individuals (19 
      females) aged 40.24+/-13.06 years were included; in G2, 22 individuals (21 females) 
      aged 64.09+/-10.01 years were included. Grade 2 mobility (p=0.031), mean probing 
      depth (p<0.001), loss of clinical insertion level (p<0.001), gingival bleeding 
      (p=0.009), and presence of palatine tori (p=0.007) were higher in G1. A higher 
      mean of tooth loss (17.90+/-13.42; p=0.031), teeth with active and/or inactive 
      caries (p<0.001), and visual change in enamel/enamel breakdown (p<0.001) were 
      also observed in G1. Most patients were 50 years old or younger, with a higher 
      prevalence of older individuals in G2 (p<0.001). G1 showed low socioeconomic 
      status and G2 medium-high status (p<0.001). CONCLUSIONS: Despite the greater 
      number of younger individuals, higher tooth loss and periodontal changes were 
      observed in G1 patients. Differences in the degree of severity of pHPTor 
      socioeconomic status alone could not explain these findings. Key words:Oral 
      health, Primary hyperparathyroidism, Multiple endocrine neoplasia type 1, 
      osteopenia, osteoporosis.
CI  - Copyright: (c) 2022 Medicina Oral S.L.
FAU - Cardoso, Fabiana-Brandao-Pain
AU  - Cardoso FB
AD  - Postgraduate Program in Pharmacology, Department of Physiology and Pharmacology, 
      Federal University of Ceara, Fortaleza, Brazil.
FAU - Costa, Fabio-Wildson-Gurgel
AU  - Costa FW
AD  - Postgraduate Program in Dentistry, Federal University of Ceara, Fortaleza, 
      Brazil.
FAU - Soares, Carlos-Eduardo-Lopes
AU  - Soares CE
AD  - Faculty of Medicine, Drug Research and Development Center (NPDM), Federal 
      University of Ceara, Fortaleza, Brazil.
FAU - de Moraes, Maria-Elisabete-Amaral
AU  - de Moraes ME
AD  - Department of Physiology and Pharmacology, Drug Research and Development Center 
      (NPDM), Faculty of Medicine, Federal University of Ceara, Fortaleza, Brazil.
FAU - D'alva, Catarina-Brasil
AU  - D'alva CB
AD  - Faculty of Medicine, Department of Clinical Medicine, Federal University of 
      Ceara, Fortaleza, Brazil.
FAU - Cavalcante, Davi-de Sa
AU  - Cavalcante DS
AD  - Postgraduate Program in Dentistry, Federal University of Ceara, Fortaleza, 
      Brazil.
FAU - Cid, Adilia-Mirela-Pereira
AU  - Cid AM
AD  - Postgraduate Program in Dentistry, Federal University of Ceara, Fortaleza, 
      Brazil.
FAU - Ribeiro, Thyciana-Rodrigues
AU  - Ribeiro TR
AD  - Postgraduate Program in Dentistry, Federal University of Ceara, Fortaleza, 
      Brazil.
FAU - Quidute, Ana-Rosa-Pinto
AU  - Quidute AR
AD  - Department of Physiology and Pharmacology, Drug Research and Development Center 
      (NPDM), Faculty of Medicine, Federal University of Ceara, Fortaleza, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20220501
PL  - Spain
TA  - J Clin Exp Dent
JT  - Journal of clinical and experimental dentistry
JID - 101603132
PMC - PMC9094720
COIS- Conflicts of interest No conflict of interest exists.
EDAT- 2022/05/19 06:00
MHDA- 2022/05/19 06:01
PMCR- 2022/05/01
CRDT- 2022/05/18 02:09
PHST- 2022/02/14 00:00 [received]
PHST- 2022/03/28 00:00 [accepted]
PHST- 2022/05/18 02:09 [entrez]
PHST- 2022/05/19 06:00 [pubmed]
PHST- 2022/05/19 06:01 [medline]
PHST- 2022/05/01 00:00 [pmc-release]
AID - 59527 [pii]
AID - 10.4317/jced.59527 [doi]
PST - epublish
SO  - J Clin Exp Dent. 2022 May 1;14(5):e396-e403. doi: 10.4317/jced.59527. eCollection 
      2022 May.