PMID- 35584379 OWN - NLM STAT- MEDLINE DCOM- 20220520 LR - 20220923 IS - 1536-4828 (Electronic) IS - 0885-3177 (Linking) VI - 51 IP - 3 DP - 2022 Mar 1 TI - Efficacy and Safety of Peroral Pancreatoscopy Through the Fistula Created by Endoscopic Ultrasound-Guided Pancreaticogastrostomy. PG - 228-233 LID - 10.1097/MPA.0000000000002003 [doi] AB - OBJECTIVES: Endoscopic ultrasound/endosonography-guided pancreaticogastrostomy (EUS-PGS) is a useful alternative when endoscopic retrograde pancreatography is difficult. Recently, many procedures, including peroral pancreatoscopy (POPS), have been performed through the mature fistula (MF) created by EUS-PGS. We evaluate the efficacy and safety of POPS to diagnose and treat pancreatic ductal stricture/pancreato-jejunal anastomotic stricture (PDS/PJAS) through the MF. METHODS: Twenty patients underwent EUS-PGS; 13 of these underwent POPS through the MF at Juntendo University Hospital. All patients were studied retrospectively in terms of technical and clinical success rates and adverse events (AEs). RESULTS: The technical and clinical success rates of EUS-PGS were 95% and 100%. The early and late AEs rates were 20% and 15%. The technical success rate of POPS was 100%, with one AE. Biopsy of PDS/PJAS under POPS guidance revealed recurrent/residual intrapapillary mucinous adenoma (3 patients) and benign fibrotic stricture (10 patients). In the latter patients, multiple plastic stents were placed to dilate PDS/PJAS. Four patients with improvement of PDS/PJAS were stent free, but the remaining patients were not yet. CONCLUSIONS: Endoscopic ultrasound/endosonography-guided pancreaticogastrostomy and various procedures (including POPS) performed through the MF are feasible and effective and can diagnose and treat PDS/PJAS with acceptable AEs rates. CI - Copyright (c) 2022 Wolters Kluwer Health, Inc. All rights reserved. FAU - Suzuki, Akinori AU - Suzuki A AD - From the Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan. FAU - Ishii, Shigeto AU - Ishii S FAU - Fujisawa, Toshio AU - Fujisawa T FAU - Saito, Hiroaki AU - Saito H FAU - Takasaki, Yusuke AU - Takasaki Y FAU - Takahashi, Sho AU - Takahashi S FAU - Yamagata, Wataru AU - Yamagata W FAU - Ochiai, Kazushige AU - Ochiai K FAU - Tomishima, Ko AU - Tomishima K FAU - Isayama, Hiroyuki AU - Isayama H LA - eng PT - Journal Article PL - United States TA - Pancreas JT - Pancreas JID - 8608542 SB - IM MH - Cholangiopancreatography, Endoscopic Retrograde/methods MH - Constriction, Pathologic MH - Drainage/methods MH - *Endosonography/methods MH - *Fistula/etiology/pathology MH - Humans MH - Pancreatic Ducts/diagnostic imaging/pathology/surgery MH - Retrospective Studies MH - Stents MH - Treatment Outcome MH - Ultrasonography, Interventional COIS- H.I. has received research grant from Fujifilm, Zeon Medical, Piolax, Boston Scientific, and Gadelius Medical and lecture fee from Fujifilm, Olympus, Zeon Medical, Century Medical, Medico's Hirata, Piolax, Cook Medical, Gadelius Medical, and Boston Scientific. The other authors declare no conflict of interest. EDAT- 2022/05/19 06:00 MHDA- 2022/05/21 06:00 CRDT- 2022/05/18 16:32 PHST- 2022/05/18 16:32 [entrez] PHST- 2022/05/19 06:00 [pubmed] PHST- 2022/05/21 06:00 [medline] AID - 00006676-202203000-00003 [pii] AID - 10.1097/MPA.0000000000002003 [doi] PST - ppublish SO - Pancreas. 2022 Mar 1;51(3):228-233. doi: 10.1097/MPA.0000000000002003.