PMID- 35600247
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2398-502X (Print)
IS  - 2398-502X (Electronic)
IS  - 2398-502X (Linking)
VI  - 6
DP  - 2021
TI  - Type 2 diabetes mellitus and anxiety symptoms: a cross-sectional study in Peru.
PG  - 331
LID - 10.12688/wellcomeopenres.17328.2 [doi]
LID - 331
AB  - BACKGROUND: Information about the effect of type 2 diabetes mellitus (T2DM) 
      awareness in the prevalence of anxiety disorders is scarce. Moreover, reports 
      from resource-constrained and semiurban settings are usually focused on 
      hospital-based data, instead of population-based surveys. We aimed to evaluate 
      the association between T2DM and anxiety symptoms, with emphasis on T2DM 
      awareness. METHODS: A secondary data analysis was conducted using information 
      from a population-based study. The outcome of interest was the presence of 
      anxiety symptoms assessed by the Goldberg anxiety test, while the exposure 
      variable was T2DM, defined using the oral glucose tolerance test. In addition, 
      another definition was used based on self-reported T2DM awareness of previous 
      diagnosis. Prevalence ratios (PR) and 95% confidence intervals (CI) were reported 
      using Poisson regression models. RESULTS: Data from 1,607 participants, of mean 
      age 48.2 (SD: 10.6) years, and 809 (50.3%) females, were analyzed. Of all 
      participants, 176 (11.0%; 95% CI: 9.5%-12.6%) had T2DM, 105 (59.7%) were aware of 
      previous diagnosis, and 674 (41.9%; 95% CI: 39.5%-44.4%) had anxiety symptoms. In 
      multivariable model, T2DM was not associated with anxiety symptoms (PR = 1.16; 
      95% CI: 0.99-1.36); however, individuals aware of T2DM diagnosis had a 36% (95% 
      CI: 14%-64%) greater prevalence of anxiety symptoms compared to those without 
      T2DM. Additionally, those aware of T2DM diagnosis had a 56% (95% CI: 13%-116%) 
      higher probability to have anxiety symptoms compared to those not aware of T2DM 
      diagnosis.   Conclusions: The association between T2DM and anxiety symptoms was 
      present among those participants who self-reported T2DM diagnosis, as opposed to 
      those with T2DM but not aware and to those without T2DM. Evaluation of anxiety 
      symptoms may be relevant among those with previous T2DM diagnosis.
CI  - Copyright: (c) 2022 Arteaga-Zarate G et al.
FAU - Arteaga-Zarate, Guadalupe
AU  - Arteaga-Zarate G
AD  - Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
FAU - Demarini-Olivares, Gina
AU  - Demarini-Olivares G
AD  - Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
FAU - Torres-Slimming, Paola A
AU  - Torres-Slimming PA
AUID- ORCID: 0000-0001-9741-9470
AD  - Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
FAU - Bernabe-Ortiz, Antonio
AU  - Bernabe-Ortiz A
AUID- ORCID: 0000-0002-6834-1376
AD  - CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano 
      Heredia, Lima, Peru.
AD  - Universidad Cientifica del Sur, Lima, Peru.
LA  - eng
SI  - figshare/10.6084/m9.figshare.16862191.v2
PT  - Journal Article
DEP - 20220513
PL  - England
TA  - Wellcome Open Res
JT  - Wellcome open research
JID - 101696457
PMC - PMC9111365
OTO - NOTNLM
OT  - Anxiety
OT  - Awareness
OT  - Peru
OT  - Type 2 diabetes mellitus
COIS- No competing interests were disclosed.
EDAT- 2022/05/25 06:00
MHDA- 2022/05/25 06:01
PMCR- 2022/05/13
CRDT- 2022/05/24 01:54
PHST- 2022/05/11 00:00 [accepted]
PHST- 2022/05/24 01:54 [entrez]
PHST- 2022/05/25 06:00 [pubmed]
PHST- 2022/05/25 06:01 [medline]
PHST- 2022/05/13 00:00 [pmc-release]
AID - 10.12688/wellcomeopenres.17328.2 [doi]
PST - epublish
SO  - Wellcome Open Res. 2022 May 13;6:331. doi: 10.12688/wellcomeopenres.17328.2. 
      eCollection 2021.