PMID- 35605133
OWN - NLM
STAT- MEDLINE
DCOM- 20220609
LR  - 20221207
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 70
IP  - 22
DP  - 2022 Jun 8
TI  - A Novel Enantioseparation Method and Enantioselective Dissipation of Novaluron in 
      Tomatoes Using Ultrahigh-Performance Liquid Chromatography Tandem Mass 
      Spectrometry via a Box-Behnken Design.
PG  - 6670-6678
LID - 10.1021/acs.jafc.2c02166 [doi]
AB  - Enantioseparation parameters of novaluron were optimized on a Chiralpak IG-3 
      column by ultrahigh-performance liquid chromatography tandem mass spectrometry 
      via response surface methodology. The absolute configuration and elution order 
      were identified as R-(+)-novaluron and S-(-)-novaluron by polarimetry and X-ray 
      diffraction. A modified QuEChERS method was developed for enantioselective 
      determination of novaluron in eight food and environmental samples. Under optimal 
      conditions, the mean recoveries of the novaluron enantiomers in the eight 
      matrices were 74.4-108.1% with intraday relative standard deviations (RSDs) of 
      0.3-9.7% and interday RSDs of 0.1-4.1%. Enantioselective dissipation was observed 
      in tomatoes. The dissipation of S-(-)-novaluron was faster than that of 
      R-(+)-novaluron with a half-life of 7.1 and 7.9 days, and the enantiomer fraction 
      value changed from 0.49 to 0.53 in 21 days. An effective method for monitoring 
      novaluron enantiomer residues in food and the environment was established for the 
      first time and had been successfully applied to real samples. This study is of 
      great significance for strengthening the risk assessment and supervision level of 
      chiral pesticides.
FAU - Li, Rui
AU  - Li R
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
FAU - Wang, Zhen
AU  - Wang Z
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
FAU - Zhang, Yanqing
AU  - Zhang Y
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
FAU - Chen, Zihao
AU  - Chen Z
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
FAU - Sang, Ningning
AU  - Sang N
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
FAU - Wang, Minghua
AU  - Wang M
AUID- ORCID: 0000-0001-5715-4981
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
FAU - Shi, Haiyan
AU  - Shi H
AD  - Department of Pesticide Science, College of Plant Protection, Nanjing 
      Agricultural University, State & Local Joint Engineering Research Center of Green 
      Pesticide Invention and Application, Nanjing 210095, China.
LA  - eng
PT  - Journal Article
DEP - 20220523
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Phenylurea Compounds)
RN  - 0 (Soil Pollutants)
RN  - Z8H1B3CW0B (novaluron)
SB  - IM
MH  - Chromatography, High Pressure Liquid/methods
MH  - *Solanum lycopersicum
MH  - Phenylurea Compounds
MH  - *Soil Pollutants/chemistry
MH  - Stereoisomerism
MH  - Tandem Mass Spectrometry/methods
OTO - NOTNLM
OT  - X-ray diffraction
OT  - enantioselective dissipation
OT  - enantioseparation
OT  - novaluron
OT  - response surface methodology
EDAT- 2022/05/24 06:00
MHDA- 2022/06/10 06:00
CRDT- 2022/05/23 15:03
PHST- 2022/05/24 06:00 [pubmed]
PHST- 2022/06/10 06:00 [medline]
PHST- 2022/05/23 15:03 [entrez]
AID - 10.1021/acs.jafc.2c02166 [doi]
PST - ppublish
SO  - J Agric Food Chem. 2022 Jun 8;70(22):6670-6678. doi: 10.1021/acs.jafc.2c02166. 
      Epub 2022 May 23.