PMID- 35607567
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 4
DP  - 2022 Apr
TI  - Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Ayahuasca Use 
      in a Satanic Ritual: A Case Report.
PG  - e24310
LID - 10.7759/cureus.24310 [doi]
LID - e24310
AB  - Ayahuasca is a psychedelic blend originating from South America that has been 
      used for hundreds of years by local tribes in ritualistic ceremonies. For the 
      last few decades, its usage has expanded to North America in various mindfulness 
      retreats that can benefit from its hallucinogenic properties. In this case 
      report, our patient had attended a satanic ritual where he had consumed copious 
      amounts of Ayahuasca over three days. Upon his return, he continued having 
      demonic hallucinations along with paranoid delusion with increasing bouts of 
      nausea and vomiting. He was brought in by first responders due to suicidal 
      ideations, and shortly after arrival, he became unresponsive with seizure-like 
      activity. The patient was evaluated to be comatose with a Glasgow Coma Scale 
      (GCS) score of 3, and upon securing the airway, was transferred to the critical 
      care unit. Laboratory results showed a case of hypoosmolar hyponatremia secondary 
      to syndrome of inappropriate antidiuretic hormone secretion (SIADH), and 
      following the supportive care, he was able to recover within four days of 
      admission. We theorize that due to the similarity in the pharmacodynamics of the 
      active compound of Ayahuasca, and drugs such as monoamine oxidase inhibitors 
      (MAOI) and 3,4-methylenedioxymethamphetamine (MDMA), it can result in SIADH in 
      its users.
CI  - Copyright (c) 2022, Bayat Mokhtari et al.
FAU - Bayat Mokhtari, Maryam
AU  - Bayat Mokhtari M
AD  - Department of Family Medicine, Larkin Community Hospital, South Miami, USA.
FAU - Bayat Mokhtari, Moein
AU  - Bayat Mokhtari M
AD  - Department of Internal Medicine, Lenox Hill Hospital, New York City, USA.
FAU - Rodriguez, Blanca Z
AU  - Rodriguez BZ
AD  - Department of Internal Medicine, Larkin Community Hospital, South Miami, USA.
FAU - Yen, Ting Yu
AU  - Yen TY
AD  - Department of Family Medicine, Larkin Community Hospital, South Miami, USA.
FAU - Rodriguez, Ivan D
AU  - Rodriguez ID
AD  - Department of Family Medicine, Larkin Community Hospital, South Miami, USA.
LA  - eng
PT  - Case Reports
DEP - 20220420
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9123388
OTO - NOTNLM
OT  - adh
OT  - ayahuasca
OT  - hallucinogens
OT  - hyponatremia
OT  - siadh
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/05/25 06:00
MHDA- 2022/05/25 06:01
PMCR- 2022/04/20
CRDT- 2022/05/24 01:59
PHST- 2022/04/20 00:00 [accepted]
PHST- 2022/05/24 01:59 [entrez]
PHST- 2022/05/25 06:00 [pubmed]
PHST- 2022/05/25 06:01 [medline]
PHST- 2022/04/20 00:00 [pmc-release]
AID - 10.7759/cureus.24310 [doi]
PST - epublish
SO  - Cureus. 2022 Apr 20;14(4):e24310. doi: 10.7759/cureus.24310. eCollection 2022 
      Apr.