PMID- 35612728 OWN - NLM STAT- MEDLINE DCOM- 20220802 LR - 20220802 IS - 2038-3312 (Electronic) IS - 2038-131X (Print) IS - 2038-131X (Linking) VI - 74 IP - 4 DP - 2022 Aug TI - Minimally invasive video-assisted parathyroidectomy (MIVAP) versus conventional parathyroidectomy for renal hyperparathyroidism: a retrospective multicenter study. PG - 1419-1428 LID - 10.1007/s13304-022-01291-9 [doi] AB - To compare minimally invasive video-assisted parathyroidectomy (MIVAP) versus conventional surgery for renal hyperparathyroidism (rHPT). Between 2006 and 2020, 53 patients underwent MIVAP and 182 underwent conventional parathyroidectomy for rHPT at the Kliniken Essen-Mitte and Knappschaftskrankenhaus Bochum, respectively. Two propensity score-matched groups were retrospectively analyzed: the MIVAP group (VG; n = 53) and the conventional group (CG; n = 53). To assess long-term results, the patients were questioned prospectively (VG; n = 17, and CG; n = 26). The VG had a smaller incision (2.8 vs. 4.8 cm), shorter operation duration (81.0 vs. 13.9 min), and shorter duration of stay (2.4 vs. 5.7 days) (p < 0.0001) but a smaller drop in parathyroid hormone (PTH) postoperatively (81.3 vs. 85.5%. p = 0.022) than the CG. The conversion rate was 9.4% (n = 5). The VG had better Patient Scar Assessment Scale (PSAS) scores (10.8 vs. 11.7 p = 0.001) but worse SF-12 health survey scores (38.7 vs. 45.8 for physical health and 46.7 vs. 53.4 for mental health) (p < 0.0001). The PTH level at follow-up was higher in the VG (162.7 vs. 59.1 ng/l, p < 0.0001). There were no differences in morbidity, number of removed parathyroid glands, disease persistence, late rHPT relapse and need for repeat surgery between groups. MIVAP was superior to conventional parathyroidectomy regarding aesthetic outcomes and cost effectiveness. Conventional surgery showed better control of PTH levels and health scores on follow-up than MIVAP, without any impact on rHPT relapse and need for repeat surgery.Trail registration number and date of registration: DRKS00022545 on 14.12.2020. CI - (c) 2022. The Author(s). FAU - Snopok, Iurii AU - Snopok I AUID- ORCID: 0000-0003-0862-5614 AD - Department of Surgery, Ruhr-University Bochum, Knappschaftskrankenhaus, Bochum, Germany. Iurii.snopok@kk-bochum.de. FAU - Viebahn, Richard AU - Viebahn R AD - Department of Surgery, Ruhr-University Bochum, Knappschaftskrankenhaus, Bochum, Germany. FAU - Walz, Martin AU - Walz M AD - Klinik Fur Chirurgie and Zentrum Fur Minimal Invasive Chirurgie, Evang, Kliniken Essen-Mitte, Essen, Germany. FAU - Zgoura, Panagiota AU - Zgoura P AD - Medical Department I, Ruhr-University Bochum, University Hospital Marienhospital Herne, Herne, Germany. FAU - Alesina, Pier Francesco AU - Alesina PF AUID- ORCID: 0000-0002-8508-9934 AD - Klinik Fur Endokrine Chirurgie, Helios University Hospital Wuppertal, Wuppertal, Germany. LA - eng GR - 1/CX/CSRD VA/United States GR - 1/CX/CSRD VA/United States PT - Journal Article PT - Multicenter Study DEP - 20220525 PL - Italy TA - Updates Surg JT - Updates in surgery JID - 101539818 SB - IM MH - Humans MH - *Hyperparathyroidism/surgery MH - Minimally Invasive Surgical Procedures/methods MH - *Parathyroidectomy/methods MH - Recurrence MH - Retrospective Studies MH - Video-Assisted Surgery/methods PMC - PMC9338138 OTO - NOTNLM OT - MIVAP OT - Parathyroidectomy OT - Propensity score matching OT - Renal hyperparathyroidism OT - Renal insufficiency OT - Retrospective COIS- The authors declare no competing interests. EDAT- 2022/05/26 06:00 MHDA- 2022/08/03 06:00 PMCR- 2022/05/25 CRDT- 2022/05/25 11:20 PHST- 2022/01/11 00:00 [received] PHST- 2022/04/03 00:00 [accepted] PHST- 2022/05/26 06:00 [pubmed] PHST- 2022/08/03 06:00 [medline] PHST- 2022/05/25 11:20 [entrez] PHST- 2022/05/25 00:00 [pmc-release] AID - 10.1007/s13304-022-01291-9 [pii] AID - 1291 [pii] AID - 10.1007/s13304-022-01291-9 [doi] PST - ppublish SO - Updates Surg. 2022 Aug;74(4):1419-1428. doi: 10.1007/s13304-022-01291-9. Epub 2022 May 25.