PMID- 3561331 OWN - NLM STAT- MEDLINE DCOM- 19870514 LR - 20170214 IS - 0094-2405 (Print) IS - 0094-2405 (Linking) VI - 14 IP - 1 DP - 1987 Jan-Feb TI - Detection efficiency of a high-pressure gas scintillation proportional chamber. PG - 115-23 AB - The detection efficiency of a high-pressure, gas scintillation proportional chamber (GSPC), designed for medical imaging in the 30-150 keV energy range, has been investigated through measurement and Monte Carlo simulation. Measurements were conducted on a GSPC containing 4 atm of pure xenon separated from a hexagonal array of seven ultraviolet-sensitive photomultiplier tubes by 1.27-cm-thick fused-silica windows. Experimental measurements of the photopeak efficiency, fluorescence escape efficiency, and the energy collection efficiency were obtained. Results were also obtained for different photon energies and different values of temporal resolution. The measurements were compared with the results obtained from a Monte Carlo simulation designed specifically for investigating the imaging of low-energy photons (below 150 keV) with a gas-filled detector. The simulation was used to estimate photopeak efficiency, fluorescence escape efficiency, photopeak-to-fluorescence escape peak ratio, quantum interaction efficiency, energy collection efficiency, and local energy collection efficiency. The photopeak efficiency of the GSPC relative to that of a 3-in. (7.62-cm)-thick sodium iodide crystal was measured to be 0.284 +/- 0.001 at 60 keV and 0.057 +/- 0.001 at 140 keV. Of the 60-keV photons incident upon the detector, 70% +/- 4% interacted in the detector, with 28% +/- 1% being in the photopeak, as estimated both by experimentation and through the simulation. The maximum energy collection efficiency was found to be 65% at 60 keV, with 46% being deposited within 0.2 cm of the initial photon interaction. The information gained from this study is being used to design an optimized detector for use in specialized nuclear medicine studies. FAU - Fahey, F H AU - Fahey FH FAU - Zimmerman, R E AU - Zimmerman RE FAU - Judy, P F AU - Judy PF FAU - Lanza, R C AU - Lanza RC LA - eng GR - R01 HL24496/HL/NHLBI NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Med Phys JT - Medical physics JID - 0425746 RN - 0 (Gases) SB - IM MH - Biophysical Phenomena MH - Biophysics MH - Gases MH - Humans MH - Monte Carlo Method MH - Pressure MH - Radionuclide Imaging/*instrumentation EDAT- 1987/01/01 00:00 MHDA- 1987/01/01 00:01 CRDT- 1987/01/01 00:00 PHST- 1987/01/01 00:00 [pubmed] PHST- 1987/01/01 00:01 [medline] PHST- 1987/01/01 00:00 [entrez] AID - 10.1118/1.596098 [doi] PST - ppublish SO - Med Phys. 1987 Jan-Feb;14(1):115-23. doi: 10.1118/1.596098.