PMID- 35620516
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2297-055X (Print)
IS  - 2297-055X (Electronic)
IS  - 2297-055X (Linking)
VI  - 9
DP  - 2022
TI  - Case Report: Giant Congenital Left Atrial Appendage Aneurysm Presenting With 
      Acute Massive Cerebral Infarction and Refractory Atrial Fibrillation: A Case 
      Report and Literature Review.
PG  - 888825
LID - 10.3389/fcvm.2022.888825 [doi]
LID - 888825
AB  - BACKGROUND: Congenital left atrial appendage aneurysm (LAAA) is a rare cardiac 
      anomaly with a variety of presentations, from being asymptomatic to potentially 
      serious complications such as systemic thromboembolism and atrial 
      tachyarrhythmia. CASE PRESENTATION: We report a case of congenital giant LAAA in 
      a 35-year-old man presenting with acute massive cerebral infarction and atrial 
      fibrillation (AF) with rapid ventricular rate. The AF was refractory to 
      conventional antiarrhythmic agents, such as amiodarone and electrical 
      cardioversion, but restored and maintained sinus rhythm after surgical resection 
      of LAAA. The patient remained free of events and was in sinus rhythm during 
      half-year follow-up. CONCLUSION: Giant LAAA has the potential causing serious 
      complications and should be managed surgically in most cases.
CI  - Copyright (c) 2022 Li, Ma, Guan, Pan, Liu, Wang and Wang.
FAU - Li, Rui
AU  - Li R
AD  - Division of Cardiology, Department of Internal Medicine, Hubei Key Laboratory of 
      Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, 
      Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 
      China.
FAU - Ma, Fei
AU  - Ma F
AD  - Division of Cardiology, Department of Internal Medicine, Hubei Key Laboratory of 
      Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, 
      Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 
      China.
FAU - Guan, Han Xiong
AU  - Guan HX
AD  - Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Pan, Yue Ying
AU  - Pan YY
AD  - Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Liu, Li Gang
AU  - Liu LG
AD  - Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical 
      College, Huazhong University of Science and Technology, Wuhan, China.
FAU - Wang, Dao Wen
AU  - Wang DW
AD  - Division of Cardiology, Department of Internal Medicine, Hubei Key Laboratory of 
      Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, 
      Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 
      China.
FAU - Wang, Hong
AU  - Wang H
AD  - Division of Cardiology, Department of Internal Medicine, Hubei Key Laboratory of 
      Genetics and Molecular Mechanism of Cardiologic Disorders, Tongji Hospital, 
      Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 
      China.
LA  - eng
PT  - Case Reports
DEP - 20220510
PL  - Switzerland
TA  - Front Cardiovasc Med
JT  - Frontiers in cardiovascular medicine
JID - 101653388
PMC - PMC9127081
OTO - NOTNLM
OT  - acute cerebral infarction
OT  - atrial fibrillation
OT  - case report
OT  - echocardiography
OT  - left atrial appendage aneurysm
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/05/28 06:00
MHDA- 2022/05/28 06:01
PMCR- 2022/01/01
CRDT- 2022/05/27 02:30
PHST- 2022/03/03 00:00 [received]
PHST- 2022/04/11 00:00 [accepted]
PHST- 2022/05/27 02:30 [entrez]
PHST- 2022/05/28 06:00 [pubmed]
PHST- 2022/05/28 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fcvm.2022.888825 [doi]
PST - epublish
SO  - Front Cardiovasc Med. 2022 May 10;9:888825. doi: 10.3389/fcvm.2022.888825. 
      eCollection 2022.