PMID- 35620547
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2398-8835 (Electronic)
IS  - 2398-8835 (Linking)
VI  - 5
IP  - 3
DP  - 2022 May
TI  - The impact of wood dust on pulmonary function and blood immunoglobulin E, 
      erythrocyte sedimentation rate, and C- reactive protein: A cross-sectional study 
      among sawmill workers in Tangail, Bangladesh.
PG  - e646
LID - 10.1002/hsr2.646 [doi]
LID - e646
AB  - BACKGROUND AND AIMS: Occupational exposure to wood dust leads to lung function 
      abnormalities that are prominent causes of morbidity and disability of sawmill 
      workers. The adverse respiratory effects of wood dust in sawmills have not been 
      studied thoroughly in Bangladesh. This study aimed to investigate the effect of 
      wood dust on the respiratory health of sawmill workers compared to controls as 
      well as to determine the association of wood dust-exposing effects with 
      inflammatory blood biomarkers, such as immunoglobulin E (IgE), erythrocyte 
      sedimentation rate (ESR), and C-reactive protein (CRP). METHODS: This 
      cross-sectional study included 100 sawmill workers from 25 distinct sawmills in 
      various areas of Tangail, Bangladesh as well as 100 healthy volunteers who were 
      adopted as a control group. Questionaries' survey and pulmonary function tests 
      were performed face to face. Furthermore, after performing lung function tests, 
      blood was drawn for further IgE, ESR, and CRP analyses. RESULTS: Respiratory 
      symptoms including breathlessness (32%), coughing (39%), sneezing (43%), chest 
      tightness (30%), and itching (40%) were significantly higher in sawmill workers 
      compared with control. Besides, sawmill workers' exposure to wood dust revealed a 
      significantly lower level of spirometry parameters (forced vital capacity 
      ​​​​​[FVC], FVC (%), forced expiratory volume in 1 s [FEV1], FEV1 (%), peak 
      expiratory flow [PEF], PEF (%), FEV1/FVC (%), FEF25, FEF75, and FEF2575) compared 
      with control and these spirometry parameters decreased with the increasing length 
      of service. Moreover, a significantly higher level of IgE was observed in sawmill 
      workers (290.90 +/- 39.49) than in the control (120.95 +/- 23.00). The high level of 
      IgE suggests that the lower pulmonary function may be linked to allergic 
      responses to wood dust among sawmill workers. CONCLUSION: This study suggested 
      that exposure to wood dust can cause impairment of respiratory function along 
      with high IgE levels.
CI  - (c) 2022 The Authors. Health Science Reports published by Wiley Periodicals LLC.
FAU - Mogal, Md Roman
AU  - Mogal MR
AUID- ORCID: 0000-0002-1349-5677
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Islam, Md Didarul
AU  - Islam MD
AUID- ORCID: 0000-0002-0521-1160
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Hasan, Md Ikbal
AU  - Hasan MI
AUID- ORCID: 0000-0002-4310-7858
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Junayed, Asadullah
AU  - Junayed A
AUID- ORCID: 0000-0001-8819-4679
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Sompa, Sagarika Adhikary
AU  - Sompa SA
AUID- ORCID: 0000-0002-2519-8952
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Mahmod, Md Rashel
AU  - Mahmod MR
AUID- ORCID: 0000-0001-6503-3311
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Akter, Aklima
AU  - Akter A
AUID- ORCID: 0000-0003-1854-4463
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
FAU - Abedin, Md Zainul
AU  - Abedin MZ
AUID- ORCID: 0000-0001-6743-9040
AD  - Department of Food Technology and Nutritional Science Mawlana Bhashani Science 
      and Technology University Bangladesh.
FAU - Sikder, Md Asaduzzaman
AU  - Sikder MA
AUID- ORCID: 0000-0003-1297-5019
AD  - Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and 
      Technology University Tangail Bangladesh.
LA  - eng
PT  - Journal Article
DEP - 20220522
PL  - United States
TA  - Health Sci Rep
JT  - Health science reports
JID - 101728855
PMC - PMC9124949
OTO - NOTNLM
OT  - IgE
OT  - respiratory health
OT  - sawmill workers
OT  - spirometry
OT  - wood dust
EDAT- 2022/05/28 06:00
MHDA- 2022/05/28 06:01
PMCR- 2022/05/22
CRDT- 2022/05/27 02:30
PHST- 2021/08/17 00:00 [received]
PHST- 2022/05/05 00:00 [revised]
PHST- 2022/05/06 00:00 [accepted]
PHST- 2022/05/27 02:30 [entrez]
PHST- 2022/05/28 06:00 [pubmed]
PHST- 2022/05/28 06:01 [medline]
PHST- 2022/05/22 00:00 [pmc-release]
AID - HSR2646 [pii]
AID - 10.1002/hsr2.646 [doi]
PST - epublish
SO  - Health Sci Rep. 2022 May 22;5(3):e646. doi: 10.1002/hsr2.646. eCollection 2022 
      May.