PMID- 35620756
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230916
IS  - 2215-0161 (Print)
IS  - 2215-0161 (Electronic)
IS  - 2215-0161 (Linking)
VI  - 9
DP  - 2022
TI  - Burst-pause criterion derivation for drinkometer measurements of ingestive 
      behavior.
PG  - 101726
LID - 10.1016/j.mex.2022.101726 [doi]
LID - 101726
AB  - The drinkometer is a promising device for the study of ingestive behavior of 
      liquid meals in humans. It can be used to investigate behavior in different 
      target populations. However, ingestive behavior has a great variability across 
      study participants. Therefore, a new analytical approach is required for the 
      extraction and analysis of drinkometer-derived data that could account for this 
      variability. We developed an optimized protocol to predict an optimal burst-pause 
      criterion (PC) for the extraction of PC-dependent microstructural parameters of 
      ingestive behavior. These describe the microstructure of bursts, while 
      PC-independent parameters describe the microstructure of sucks. Therefore, a PC 
      is required to analyze separately two physiologically different parts of 
      behavior. To accomplish this burst-pause criterion derivation (BPCD), a Gaussian 
      Mixture Model (GMM) was built for estimation of two probability density functions 
      (PDFs). These model the distribution of inter-suck intervals (ISIs) and 
      inter-burst intervals (IBIs), respectively. The PC is defined at the intersection 
      point of the two density functions. A Kaplan-Meier (KM) survival analysis was 
      performed for post-hoc verification of the fit of the predicted optimal PC to the 
      ISI distribution. In this protocol paper, we present a walkthrough of the data 
      analysis of drinkometer-derived data for the measurement of microstructure of 
      ingestive behavior based on previous results published by our group 
      [1].*Standardization of the burst-pause criterion derivation for drinkometer 
      measurements of ingestive behavior.*All codes are publicly available in a 
      repository.*The method can be easily adapted to studies with larger sample size 
      or more than one study stimulus.
CI  - (c) 2022 Published by Elsevier B.V.
FAU - Serra, Michele
AU  - Serra M
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - File, Balint
AU  - File B
AD  - Faculty of Information Technology and Bionics, Pazmany Peter Catholic University, 
      Budapest, Hungary.
AD  - Wigner Research Centre for Physics, Budapest, Hungary.
FAU - Alceste, Daniela
AU  - Alceste D
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Raguz, Ivana
AU  - Raguz I
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Gero, Daniel
AU  - Gero D
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Thalheimer, Andreas
AU  - Thalheimer A
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Widmer, Jeannette
AU  - Widmer J
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Ismaeil, Aiman
AU  - Ismaeil A
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Steinert, Robert E
AU  - Steinert RE
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
FAU - Spector, Alan C
AU  - Spector AC
AD  - Department of Psychology and Program in Neuroscience, Florida State University, 
      Tallahassee, FL, USA.
FAU - Bueter, Marco
AU  - Bueter M
AD  - Department of Surgery and Transplantation, University Hospital Zurich, 
      Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20220511
PL  - Netherlands
TA  - MethodsX
JT  - MethodsX
JID - 101639829
PMC - PMC9127353
OTO - NOTNLM
OT  - Burst-pause criterion
OT  - Drinkometer
OT  - Ingestive behavior
OT  - Obesity
OT  - Weight loss
EDAT- 2022/05/28 06:00
MHDA- 2022/05/28 06:01
PMCR- 2022/05/11
CRDT- 2022/05/27 02:34
PHST- 2022/02/23 00:00 [received]
PHST- 2022/05/05 00:00 [accepted]
PHST- 2022/05/27 02:34 [entrez]
PHST- 2022/05/28 06:00 [pubmed]
PHST- 2022/05/28 06:01 [medline]
PHST- 2022/05/11 00:00 [pmc-release]
AID - S2215-0161(22)00107-8 [pii]
AID - 101726 [pii]
AID - 10.1016/j.mex.2022.101726 [doi]
PST - epublish
SO  - MethodsX. 2022 May 11;9:101726. doi: 10.1016/j.mex.2022.101726. eCollection 2022.