PMID- 35627036
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 11
IP  - 10
DP  - 2022 May 18
TI  - Anti-Diabetic Activity of Polysaccharides from Auricularia cornea var. Li.
LID - 10.3390/foods11101464 [doi]
LID - 1464
AB  - Auricularia cornea var. Li. polysaccharide (ACP) has many important biological 
      activities and has potential application value in food engineering, 
      pharmaceutical science, and health care. The results were as follows: the 
      extraction rate of ACP was 28.18% +/- 1.41% and the purity of ACP was 86.92% +/- 
      2.80%. ACP contains mannitol 32.41%, glucuronic acid 6.96%, rhamnose 0.32%, 
      glucose 42.35%, galactose 0.77%, xylose 16.83%, and fucose 0.36%, without 
      galacturonic acid and arabinose. In addition, the results of an animal test of 
      diabetes mellitus II (DM II) with ACP showed that the total cholesterol (TC), 
      triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and fasting blood 
      glucose and water in the serum of mice with ACP were significantly lower than 
      those in the model group; the serum SOD, hepatic glycogen, and insulin of mice 
      added with ACP were significantly higher than those in the model group. More 
      importantly, ACP had no significant adverse effects on organ index and liver and 
      kidney tissue morphology in mice. These results suggest that ACP can be used as a 
      potential functional food component for the prevention or treatment of diabetes.
FAU - Fu, Yuan
AU  - Fu Y
AD  - College of Food Science and Engineering, Jilin Agricultural University, 2888 
      Xincheng Street, Changchun 130118, China.
FAU - Wang, Liwen
AU  - Wang L
AD  - China South Korea (Changchun) International Cooperation Demonstration Zone 
      Management Committee, Changchun 130042, China.
FAU - Jiang, Guochuan
AU  - Jiang G
AD  - College of Food Science and Engineering, Jilin Agricultural University, 2888 
      Xincheng Street, Changchun 130118, China.
FAU - Ren, Lili
AU  - Ren L
AUID- ORCID: 0000-0003-1997-1010
AD  - Key Laboratory of Bionic Engineering (Ministry of Education), College of 
      Biological and Agricultural Engineering, Jilin University, 5988 Renmin Street, 
      Changchun 130022, China.
FAU - Wang, Liyan
AU  - Wang L
AUID- ORCID: 0000-0002-3744-7901
AD  - College of Food Science and Engineering, Jilin Agricultural University, 2888 
      Xincheng Street, Changchun 130118, China.
FAU - Liu, Xuejun
AU  - Liu X
AD  - College of Food Science and Engineering, Jilin Agricultural University, 2888 
      Xincheng Street, Changchun 130118, China.
LA  - eng
PT  - Journal Article
DEP - 20220518
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC9140784
OTO - NOTNLM
OT  - Auricularia cornea var. Li.
OT  - diabetes mellitus II
OT  - polysaccharides
COIS- The authors declare no conflict of interest.
EDAT- 2022/05/29 06:00
MHDA- 2022/05/29 06:01
PMCR- 2022/05/18
CRDT- 2022/05/28 01:14
PHST- 2022/04/21 00:00 [received]
PHST- 2022/05/12 00:00 [revised]
PHST- 2022/05/16 00:00 [accepted]
PHST- 2022/05/28 01:14 [entrez]
PHST- 2022/05/29 06:00 [pubmed]
PHST- 2022/05/29 06:01 [medline]
PHST- 2022/05/18 00:00 [pmc-release]
AID - foods11101464 [pii]
AID - foods-11-01464 [pii]
AID - 10.3390/foods11101464 [doi]
PST - epublish
SO  - Foods. 2022 May 18;11(10):1464. doi: 10.3390/foods11101464.