PMID- 35628843
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 11
IP  - 10
DP  - 2022 May 11
TI  - Non-Invasive Cardiac Output Determination Using Magnetic Resonance Imaging and 
      Thermodilution in Pulmonary Hypertension.
LID - 10.3390/jcm11102717 [doi]
LID - 2717
AB  - Magnetic resonance imaging (MRI) can be used to measure cardiac output (CO) 
      non-invasively, which is a paramount parameter in pulmonary hypertension (PH) 
      patients. We retrospectively compared stroke volume (SV) obtained with MRI 
      (SV(MRI)) in six localisations against SV measured with thermodilution (TD) 
      (SV(TD)) and against each other in 24 patients evaluated in our PH centre using 
      Bland and Altman (BA) agreement analyses, linear correlation, and intraclass 
      correlation (ICC). None of the six tested localisations for SV(MRI) reached the 
      predetermined criteria for interchangeability with SV(TD), with two standard 
      deviations (2SD) of bias between 24.1 mL/beat and 31.1 mL/beat. The SV(MRI) 
      methods yielded better agreement when compared against each other than the 
      comparison between SV(MRI) and SV(TD), with the best 2SD of bias being 13.8 
      mL/beat. The inter-observer and intra-observer ICCs for CO(MRI) were excellent 
      (inter-observer ICC between 0.889 and 0.983 and intra-observer ICC between 0.991 
      and 0.999). We could not confirm the interchangeability of SV(MRI) with SV(TD) 
      based on the predetermined interchangeability criteria. The lack of agreement 
      between MRI and TD might be explained because TD is less precise than previously 
      thought. We evaluated a new method to estimate CO through the pulmonary 
      circulation (COp) in PH patients that may be more precise than the previously 
      tested methods.
FAU - Crowe, Lindsey A
AU  - Crowe LA
AD  - Division of Radiology, Diagnostic Department, Geneva University Hospitals, 1205 
      Geneva, Switzerland.
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
FAU - Genecand, Leon
AU  - Genecand L
AUID- ORCID: 0000-0001-6965-0480
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
AD  - Pulmonary Hypertension Program, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
AD  - Division of Pulmonary Medicine, Department of Medicine, Geneva University 
      Hospitals, 1205 Geneva, Switzerland.
FAU - Hachulla, Anne-Lise
AU  - Hachulla AL
AD  - Division of Radiology, Diagnostic Department, Geneva University Hospitals, 1205 
      Geneva, Switzerland.
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
AD  - Pulmonary Hypertension Program, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
FAU - Noble, Stephane
AU  - Noble S
AUID- ORCID: 0000-0002-8018-2857
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
AD  - Pulmonary Hypertension Program, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
AD  - Division of Cardiology, Department of Medicine, Geneva University Hospitals, 1205 
      Geneva, Switzerland.
FAU - Beghetti, Maurice
AU  - Beghetti M
AUID- ORCID: 0000-0002-1841-0927
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
AD  - Pulmonary Hypertension Program, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
AD  - Paediatric Cardiology Unit, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
AD  - Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pediatrique, 
      University of Geneva and Lausanne, 1205 Geneva, Switzerland.
FAU - Vallee, Jean-Paul
AU  - Vallee JP
AD  - Division of Radiology, Diagnostic Department, Geneva University Hospitals, 1205 
      Geneva, Switzerland.
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
AD  - Pulmonary Hypertension Program, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
FAU - Lador, Frederic
AU  - Lador F
AD  - Faculty of Medicine, University of Geneva, 1205 Geneva, Switzerland.
AD  - Pulmonary Hypertension Program, Geneva University Hospitals, 1205 Geneva, 
      Switzerland.
AD  - Division of Pulmonary Medicine, Department of Medicine, Geneva University 
      Hospitals, 1205 Geneva, Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20220511
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC9143884
OTO - NOTNLM
OT  - cardiac output
OT  - magnetic resonance imaging
OT  - pulmonary hypertension
OT  - thermodilution
COIS- L.A.C. has nothing to disclose. L.G. has nothing to disclose. A.-L.H. has nothing 
      to disclose. S.N. has nothing to disclose. M.B. reports grants and personal fees 
      from Actelion/Janssen, grants and personal fees from Bayer, personal fees from 
      Acceleron, personal fees from Altavant, personal fees from Orpha, personal fees 
      from Gossamer, and personal fees from GSK outside the submitted work. J.-P.V. has 
      nothing to disclose. F.L. reports personal fees from Actelion/janssen, personal 
      fees from OrphaSwiss, and personal fees from MSD outside the submitted work.
EDAT- 2022/05/29 06:00
MHDA- 2022/05/29 06:01
PMCR- 2022/05/11
CRDT- 2022/05/28 01:24
PHST- 2022/04/19 00:00 [received]
PHST- 2022/04/30 00:00 [revised]
PHST- 2022/05/09 00:00 [accepted]
PHST- 2022/05/28 01:24 [entrez]
PHST- 2022/05/29 06:00 [pubmed]
PHST- 2022/05/29 06:01 [medline]
PHST- 2022/05/11 00:00 [pmc-release]
AID - jcm11102717 [pii]
AID - jcm-11-02717 [pii]
AID - 10.3390/jcm11102717 [doi]
PST - epublish
SO  - J Clin Med. 2022 May 11;11(10):2717. doi: 10.3390/jcm11102717.