PMID- 35630471
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2076-2607 (Print)
IS  - 2076-2607 (Electronic)
IS  - 2076-2607 (Linking)
VI  - 10
IP  - 5
DP  - 2022 May 15
TI  - Relationship of the Difficulty of Helicobacter pylori Eradication with Drinking 
      Habits and Allergic Disease.
LID - 10.3390/microorganisms10051029 [doi]
LID - 1029
AB  - Eradication of Helicobacter pylori (H. pylori) is crucial to reduce the risk of 
      developing gastric ulcers and gastric cancer. Although immunoglobulin E (IgE) 
      levels and alcohol consumption have been shown to influence the failure of H. 
      pylori eradication, the relationship between these factors and the mechanism of 
      failure has not been clarified. Because high IgE levels are associated with 
      eradication failure, the purpose of this study was to clarify the factors leading 
      to high IgE levels. Completed questionnaires and blood test data were collected 
      from patients who visited a university hospital for H. pylori eradication. 
      Logistic regression analysis was per-formed to examine the relationship between 
      high IgE levels and allergic diseases. We also examined the relationship between 
      alcohol intake and high IgE levels. Linear regression analysis was performed on 
      the relationship between the amount of alcohol consumed and IgE measurements. The 
      results showed that patients with allergic diseases and those with high alcohol 
      intake had significantly higher IgE levels. High IgE levels are a risk factor for 
      failure of H. pylori eradication that is associated with drinking habits and 
      alcohol consumption, and our results suggest that daily alcohol consumption 
      should be avoided even in non-allergic patients.
FAU - Ozeki, Kayoko
AU  - Ozeki K
AD  - Laboratory of Pharmacy Practice and Sciences, Aichi Gakuin University, Nagoya 
      4648650, Aichi, Japan.
AD  - Department of Community Health and Preventive Medicine, Hamamatsu University 
      School of Medicine, Hamamatsu 4313192, Shizuoka, Japan.
FAU - Furuta, Takahisa
AU  - Furuta T
AD  - Center for Clinical Research, Hamamatsu University School of Medicine, Hamamatsu 
      4313192, Shizuoka, Japan.
FAU - Hada, Kazuhiro
AU  - Hada K
AD  - Laboratory of Pharmacy Practice and Sciences, Aichi Gakuin University, Nagoya 
      4648650, Aichi, Japan.
FAU - Wakiya, Yoshifumi
AU  - Wakiya Y
AD  - Laboratory of Pharmacy Practice and Sciences, Aichi Gakuin University, Nagoya 
      4648650, Aichi, Japan.
FAU - Ojima, Toshiyuki
AU  - Ojima T
AD  - Department of Community Health and Preventive Medicine, Hamamatsu University 
      School of Medicine, Hamamatsu 4313192, Shizuoka, Japan.
LA  - eng
GR  - n/a/Aichi-Gakuin University, Institute of Medical Pharmacy and Life Sciences./
PT  - Journal Article
DEP - 20220515
PL  - Switzerland
TA  - Microorganisms
JT  - Microorganisms
JID - 101625893
PMC - PMC9147128
OTO - NOTNLM
OT  - Helicobacter pylori
OT  - alcohol
OT  - eradication
OT  - immunoglobulin E levels
COIS- The authors declare no conflict of interest.
EDAT- 2022/05/29 06:00
MHDA- 2022/05/29 06:01
PMCR- 2022/05/15
CRDT- 2022/05/28 01:33
PHST- 2022/04/23 00:00 [received]
PHST- 2022/05/04 00:00 [revised]
PHST- 2022/05/12 00:00 [accepted]
PHST- 2022/05/28 01:33 [entrez]
PHST- 2022/05/29 06:00 [pubmed]
PHST- 2022/05/29 06:01 [medline]
PHST- 2022/05/15 00:00 [pmc-release]
AID - microorganisms10051029 [pii]
AID - microorganisms-10-01029 [pii]
AID - 10.3390/microorganisms10051029 [doi]
PST - epublish
SO  - Microorganisms. 2022 May 15;10(5):1029. doi: 10.3390/microorganisms10051029.