PMID- 35646241 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230427 IS - 1945-7928 (Print) IS - 1945-8452 (Electronic) IS - 1945-7928 (Linking) VI - 2022 DP - 2022 Mar TI - MAXIMIZING UNAMBIGUOUS VELOCITY RANGE IN PHASE-CONTRAST MRI WITH MULTIPOINT ENCODING. LID - 10.1109/isbi52829.2022.9761589 [doi] AB - In phase-contrast magnetic resonance imaging (PC-MRI), the velocity of spins at a voxel is encoded in the image phase. The strength of the velocity encoding gradient offers a trade-off between the velocity-to-noise ratio (VNR) and the extent of phase aliasing. Phase differences provide invariance to an unknown background phase. Existing literature proposes processing a reduced set of phase difference equations, simplifying the phase unwrapping problem at the expense of VNR or unaliased range of velocities, or both. Here, we demonstrate that the fullest unambiguous range of velocities is a parallelepiped, which can be accessed by jointly processing all phase differences. The joint processing also maximizes the velocity-to-noise ratio. The simple understanding of the unambiguous parallelepiped provides the potential for analyzing new multi-point acquisitions for an enhanced range of unaliased velocities; two examples are given. FAU - Zhao, Shen AU - Zhao S AD - The Ohio State University, Department of Electrical and Computer Engineering. FAU - Ahmad, Rizwan AU - Ahmad R AD - The Ohio State University, Department of Electrical and Computer Engineering. AD - The Ohio State University, Department of Biomedical Engineering. FAU - Potter, Lee C AU - Potter LC AD - The Ohio State University, Department of Electrical and Computer Engineering. LA - eng GR - R01 HL135489/HL/NHLBI NIH HHS/United States GR - R01 HL151697/HL/NHLBI NIH HHS/United States PT - Journal Article DEP - 20220426 PL - United States TA - Proc IEEE Int Symp Biomed Imaging JT - Proceedings. IEEE International Symposium on Biomedical Imaging JID - 101492570 PMC - PMC9136874 MID - NIHMS1809822 OTO - NOTNLM OT - Phase-contrast imaging OT - multivariate congruence equations OT - phase unwrapping EDAT- 2022/06/02 06:00 MHDA- 2022/06/02 06:01 PMCR- 2023/04/26 CRDT- 2022/06/01 11:34 PHST- 2022/06/01 11:34 [entrez] PHST- 2022/06/02 06:00 [pubmed] PHST- 2022/06/02 06:01 [medline] PHST- 2023/04/26 00:00 [pmc-release] AID - 10.1109/isbi52829.2022.9761589 [doi] PST - ppublish SO - Proc IEEE Int Symp Biomed Imaging. 2022 Mar;2022:10.1109/isbi52829.2022.9761589. doi: 10.1109/isbi52829.2022.9761589. Epub 2022 Apr 26.