PMID- 35647838 OWN - NLM STAT- MEDLINE DCOM- 20220603 LR - 20220724 IS - 2284-0729 (Electronic) IS - 1128-3602 (Linking) VI - 26 IP - 10 DP - 2022 May TI - A short review on cervical cancer cell lines characterization and their corresponding human leukocyte antigen (HLA) type expression. PG - 3570-3576 LID - 28852 [pii] LID - 10.26355/eurrev_202205_28852 [doi] AB - Cervical cancer is one of the leading causes of death in women worldwide. Extensive research is ongoing to develop efficient diagnostics and therapeutic approaches for cervical cancer, which rely on the preliminary studies based on cervical cell lines. It is essential to characterize these cell lines to ensure the suitability of the cells for each study. In this review, the human leukocyte antigen (HLA) molecule expressed on each cervical cancer line is presented. HLA characterization of the cervical cancer cell lines is essential to increase the specificity of treatment towards certain type of cervical cancer, allowing accurate therapy. HLA characterization is also important for the generation of novel diagnostics and/or therapeutics molecules, especially for HLA-based strategies. FAU - Rajan, R S AU - Rajan RS AD - Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, Malaysia. venugopal@usm.my. FAU - Dass, S A AU - Dass SA FAU - Tye, G J AU - Tye GJ FAU - Balakrishnan, V AU - Balakrishnan V LA - eng PT - Journal Article PT - Review PL - Italy TA - Eur Rev Med Pharmacol Sci JT - European review for medical and pharmacological sciences JID - 9717360 RN - 0 (HLA Antigens) SB - IM MH - Cell Line, Tumor MH - Female MH - *HLA Antigens/genetics MH - Humans MH - *Uterine Cervical Neoplasms/genetics EDAT- 2022/06/02 06:00 MHDA- 2022/06/07 06:00 CRDT- 2022/06/01 11:59 PHST- 2022/06/01 11:59 [entrez] PHST- 2022/06/02 06:00 [pubmed] PHST- 2022/06/07 06:00 [medline] AID - 28852 [pii] AID - 10.26355/eurrev_202205_28852 [doi] PST - ppublish SO - Eur Rev Med Pharmacol Sci. 2022 May;26(10):3570-3576. doi: 10.26355/eurrev_202205_28852.