PMID- 35647858 OWN - NLM STAT- MEDLINE DCOM- 20220603 LR - 20220804 IS - 2284-0729 (Electronic) IS - 1128-3602 (Linking) VI - 26 IP - 10 DP - 2022 May TI - Pulmonary embolism in patients with dyspnea after COVID-19 infection. PG - 3751-3759 LID - 28872 [pii] LID - 10.26355/eurrev_202205_28872 [doi] AB - OBJECTIVE: Pulmonary embolism as a potential complication that may occur late in the course of COVID-19 cases. The aim of our study is to evaluate the frequency of pulmonary embolism in patients with new or ongoing dyspnea after a COVID-19 infection. PATIENTS AND METHODS: This is a single-center, prospective observational study to evaluate the clinical and radiological outcomes of consecutive patients presenting outpatient clinic diseases to the chest and a new or ongoing dyspnea after a COVID-19 infection. Demographic, clinical and laboratory data were collected. Dyspnea was evaluated according to the New York Heart Association (NYHA) classification. RESULTS: Pulmonary embolism was detected in 23.8% (25/105) of patients with new or ongoing dyspnea after a COVID-19 infection. Proportion of pulmonary embolism in patients with NYHA classes I, II, III and IV were respectively 8.7%, 20.0%, 30.0% and 35.3% (p for trend=0.02). Compared to NYHA class I and II patients with dyspnea, those in NYHA classes III and IV showed a higher rate of pulmonary embolism [31.6% vs. 14.6%, OR: 2.7 (1.0 to 7.1), p=0.04, respectively]. In Logistic Procedures, NYHA classes of dyspnea (OR: 4.3, 95% CI: 1.2 to 16.6, p=0.03) (NYHA class III and IV vs. NYHA class I and II) determine the likelihood of pulmonary embolism after COVID-19 infection. CONCLUSIONS: Pulmonary embolism is common in patients with new or ongoing shortness of breath after a COVID-19 infection. Pulmonary embolism is more likely to develop in patients with higher NYHA classes. FAU - Ekici, A AU - Ekici A AD - Department of Chest Diseases, Kirikkale University Faculty of Medicine, Yahsihan, Kirikkale, Turkey. mehmetekici_@hotmail.com. FAU - Ekici, M AU - Ekici M FAU - Baccioglu, A AU - Baccioglu A FAU - Akyuz Inanc, F AU - Akyuz Inanc F FAU - Aslan, H AU - Aslan H LA - eng PT - Journal Article PT - Observational Study PL - Italy TA - Eur Rev Med Pharmacol Sci JT - European review for medical and pharmacological sciences JID - 9717360 SB - IM MH - *COVID-19/complications MH - Dyspnea/epidemiology/etiology MH - Humans MH - Prospective Studies MH - *Pulmonary Embolism/complications/etiology EDAT- 2022/06/02 06:00 MHDA- 2022/06/07 06:00 CRDT- 2022/06/01 11:59 PHST- 2022/06/01 11:59 [entrez] PHST- 2022/06/02 06:00 [pubmed] PHST- 2022/06/07 06:00 [medline] AID - 28872 [pii] AID - 10.26355/eurrev_202205_28872 [doi] PST - ppublish SO - Eur Rev Med Pharmacol Sci. 2022 May;26(10):3751-3759. doi: 10.26355/eurrev_202205_28872.