PMID- 35650134 OWN - NLM STAT- MEDLINE DCOM- 20230105 LR - 20230203 IS - 1349-7235 (Electronic) IS - 0918-2918 (Print) IS - 0918-2918 (Linking) VI - 62 IP - 1 DP - 2023 Jan 1 TI - Muscle Biopsy-proven Drug-induced Microscopic Polyangiitis in a Patient with Tuberculosis. PG - 129-133 LID - 10.2169/internalmedicine.9599-22 [doi] AB - We herein report a case of muscle biopsy-proven microscopic polyangiitis (MPA) in a patient with tuberculosis. The patient had developed a persistent fever after the initiation of treatment for tuberculosis and was positive for myeloperoxidase-antineutrophil cytoplasmic antibody (ANCA). However, because conventional symptoms were lacking, determination of the biopsy site was difficult. Based on the findings of a biopsy of the biceps femoris, which confirmed small vessel vasculitis, the patient was diagnosed with MPA. The fever was alleviated by glucocorticoids. Tuberculosis and antituberculosis drugs can cause ANCA-associated vasculitis (AAV). A muscle biopsy is useful for the diagnosis of AAV. FAU - Kuwabara, Gaku AU - Kuwabara G AD - Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Japan. AD - Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Japan. FAU - Yamada, Koichi AU - Yamada K AD - Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Japan. FAU - Tanaka, Kiyomi AU - Tanaka K AD - Post Graduate Medical Training Center, Osaka City University Hospital, Japan. FAU - Nozuchi, Satoshi AU - Nozuchi S AD - Department of Neurology, Graduate School of Medicine, Osaka City University, Japan. FAU - Imoto, Waki AU - Imoto W AD - Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Japan. FAU - Shibata, Wataru AU - Shibata W AD - Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Japan. FAU - Tohda, Mitsunori AU - Tohda M AD - Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Japan. FAU - Kyoh, Shigenori AU - Kyoh S AD - Department of Respiratory Medicine, Wakakusa-Daiichi Hospital, Japan. FAU - Itoh, Yoshiaki AU - Itoh Y AD - Department of Neurology, Graduate School of Medicine, Osaka City University, Japan. FAU - Hashimoto, Motomu AU - Hashimoto M AD - Department of Clinical Immunology, Graduate School of Medicine, Osaka City University, Japan. FAU - Kakeya, Hiroshi AU - Kakeya H AD - Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20220531 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (Antibodies, Antineutrophil Cytoplasmic) SB - IM MH - Humans MH - *Microscopic Polyangiitis/complications/diagnosis/drug therapy MH - *Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis MH - Antibodies, Antineutrophil Cytoplasmic MH - *Tuberculosis MH - Biopsy MH - Muscles/pathology MH - *Granulomatosis with Polyangiitis PMC - PMC9876704 OTO - NOTNLM OT - antineutrophil cytoplasmic antibody OT - antineutrophil cytoplasmic antibody-associated vasculitis OT - microscopic polyangiitis OT - muscle biopsy OT - tuberculosis COIS- The authors state that they have no Conflict of Interest (COI). EDAT- 2022/06/02 06:00 MHDA- 2023/01/06 06:00 PMCR- 2023/01/01 CRDT- 2022/06/01 22:34 PHST- 2022/06/02 06:00 [pubmed] PHST- 2023/01/06 06:00 [medline] PHST- 2022/06/01 22:34 [entrez] PHST- 2023/01/01 00:00 [pmc-release] AID - 10.2169/internalmedicine.9599-22 [doi] PST - ppublish SO - Intern Med. 2023 Jan 1;62(1):129-133. doi: 10.2169/internalmedicine.9599-22. Epub 2022 May 31.