PMID- 35652164
OWN - NLM
STAT- MEDLINE
DCOM- 20220713
LR  - 20220803
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 100
IP  - 1
DP  - 2022 Jul
TI  - Procedural results and in-hospital outcomes of percutaneous coronary intervention 
      for chronic total occlusion in patients with reduced left ventricular ejection 
      fraction: Sub-analysis of the Japanese CTO-PCI Expert Registry.
PG  - 30-39
LID - 10.1002/ccd.30231 [doi]
AB  - OBJECTIVES: To evaluate the procedural results and in-hospital outcomes of 
      percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in 
      patients with reduced left ventricular ejection fraction (LVEF). BACKGROUND: 
      While the technical success of general CTO-PCI has improved, CTO-PCI patients 
      with reduced LVEF remain at high-risk for adverse events. METHODS: The data of 
      820 patients with LVEF </= 35% (Group 1), 1816 patients with LVEF = 35%-50% (Group 
      2), and 5503 patients with LVEF >/= 50% (Group 3), registered in the Japanese 
      CTO-PCI Expert Registry from January 2014 to December 2019, were retrospectively 
      analyzed. The primary endpoint was in-hospital major adverse cardiac or 
      cerebrovascular events (MACCEs), including death, myocardial infarction, stent 
      thrombosis, stroke, and emergent revascularization. Secondary endpoints included 
      procedural details, guidewire success, and technical success. RESULTS: There were 
      no differences in guidewire and technical success rates between the groups. 
      In-hospital MACCEs was significantly higher in Group 1 (Group 1 vs. Group 2 vs. 
      Group 3: 3.4% vs. 1.7% vs. 1.5%, p = 0.001) and was especially driven by death 
      (1.3% vs. 0.3% vs. 0.1%, p < 0.001) and stroke (0.7% vs. 0.2% vs. 
      0.2%, p = 0.007). Multivariate analysis showed that LVEF </= 35% (odds 
      ratio [OR]; 1.58, 95% confidence interval [CI]; 1.04-2.41, p = 0.03) and New York 
      Heart Association (NYHA) class >/= 3 (OR; 2.01, 95% CI; 1.03-3.93, p = 0.04) were 
      predictors of in-hospital MACCEs. CONCLUSIONS: In-hospital MACCEs were 
      significantly higher in patients with LVEF </= 35%. LVEF </=;35% and NYHA class >/= 3 
      were predictors of in-hospital MACCEs after CTO-PCI.
CI  - (c) 2022 Wiley Periodicals LLC.
FAU - Kobayashi, Norihiro
AU  - Kobayashi N
AUID- ORCID: 0000-0003-1254-0621
AD  - Department of Cardiology, Saiseikai Yokohama City Eastern Hospital, Yokohama, 
      Japan.
FAU - Ito, Yoshiaki
AU  - Ito Y
AD  - Department of Cardiology, Saiseikai Yokohama City Eastern Hospital, Yokohama, 
      Japan.
FAU - Kishi, Koichi
AU  - Kishi K
AD  - Department of Cardiology, Tokushima Red Cross Hospital, Komatsushima, Japan.
FAU - Muramatsu, Toshiya
AU  - Muramatsu T
AD  - Department of Cardiology, Tokyo Heart Center, Shinagawa-ku, Japan, Tokyo.
FAU - Okada, Hisayuki
AU  - Okada H
AD  - Department of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, 
      Japan.
FAU - Oikawa, Yuji
AU  - Oikawa Y
AD  - Department of Cardiovascular Medicine, the Cardiovascular Institute, Tokyo, 
      Japan.
FAU - Kawasaki, Tomohiro
AU  - Kawasaki T
AUID- ORCID: 0000-0002-4795-7745
AD  - Department of Cardiology, Shin-Koga Hospital, Kurume, Japan.
FAU - Yoshikawa, Ryohei
AU  - Yoshikawa R
AD  - Cardiology Center, Sanda City Hospital, Sanda, Japan.
FAU - Tanaka, Hiroyuki
AU  - Tanaka H
AD  - Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Okayama, Japan.
FAU - Katoh, Osamu
AU  - Katoh O
AD  - Japanese CTO-PCI Expert Foundation, Kurashiki, Japan.
LA  - eng
GR  - Medtronic Japan/
GR  - Nipro/
GR  - Abbott Japan/
GR  - Biosensors Japan/
GR  - Boston Scientific Japan/
GR  - Kaneka/
GR  - Daiichi Sankyo Company/
GR  - Asahi Intecc/
GR  - Terumo/
PT  - Journal Article
DEP - 20220601
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Chronic Disease
MH  - *Coronary Occlusion/diagnostic imaging/etiology/therapy
MH  - Hospitals
MH  - Humans
MH  - Japan
MH  - *Percutaneous Coronary Intervention/adverse effects/methods
MH  - Registries
MH  - Retrospective Studies
MH  - Risk Factors
MH  - *Stroke/etiology
MH  - Stroke Volume
MH  - Treatment Outcome
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - chronic total occlusion
OT  - left ventricular ejection fraction
OT  - major adverse cardiac or cerebrovascular events
OT  - percutaneous coronary intervention
EDAT- 2022/06/03 06:00
MHDA- 2022/07/14 06:00
CRDT- 2022/06/02 03:03
PHST- 2022/04/06 00:00 [revised]
PHST- 2021/11/22 00:00 [received]
PHST- 2022/05/03 00:00 [accepted]
PHST- 2022/06/03 06:00 [pubmed]
PHST- 2022/07/14 06:00 [medline]
PHST- 2022/06/02 03:03 [entrez]
AID - 10.1002/ccd.30231 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2022 Jul;100(1):30-39. doi: 10.1002/ccd.30231. Epub 
      2022 Jun 1.