PMID- 35653074 OWN - NLM STAT- MEDLINE DCOM- 20220822 LR - 20221006 IS - 0973-7693 (Electronic) IS - 0019-5456 (Linking) VI - 89 IP - 9 DP - 2022 Sep TI - Imaging in Pediatric Obstructive Jaundice. PG - 899-907 LID - 10.1007/s12098-022-04171-7 [doi] AB - Cholestatic jaundice characterized by elevated conjugated bilirubin can be due to multitude of factors in neonates and childhood. Extrahepatic biliary atresia (EHBA), choledochal cyst, neonatal hepatitis, cytomegalovirus (CMV), and biliary plug are some of the common causes in neonate and early infancy. Causes in late infancy and childhood comprises viral hepatitis, choledochal cyst, cholelithiasis, worm infestation, and biliary compression secondary to extrinsic causes (node, collection, tumor). Some serious disorders like biliary atresia must be considered with the emphasis on early diagnosis of treatable causes. In the modern era, with multiple diagnostic modalities available including high-resolution ultrasonography, magnetic resonance imaging (MRI), CT scan, and nuclear imaging [hepatobiliary iminodiacetic acid (HIDA) scan], rapid diagnosis can be made in many surgically treatable cases. The authors will discuss the imaging modality available with advantages, disadvantages, and common indications of each modality, and overview of obstructive jaundice discussing the wide spectrum of causes in neonates and late childhood. Combining available knowledge with careful and meticulous search can help narrow down the diagnosis and initiate prompt treatment. CI - (c) 2022. The Author(s), under exclusive licence to Dr. K C Chaudhuri Foundation. FAU - Jain, Rupali AU - Jain R AD - Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. FAU - Gupta, Amit AU - Gupta A AD - Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. FAU - Kandasamy, Devasenathipathy AU - Kandasamy D AD - Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. FAU - Jana, Manisha AU - Jana M AUID- ORCID: 0000-0001-7449-6596 AD - Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India. manishajana@gmail.com. LA - eng PT - Journal Article PT - Review DEP - 20220602 PL - India TA - Indian J Pediatr JT - Indian journal of pediatrics JID - 0417442 SB - IM MH - *Biliary Atresia/diagnosis/diagnostic imaging MH - *Biliary Tract MH - *Choledochal Cyst/diagnosis/diagnostic imaging MH - Humans MH - Infant, Newborn MH - *Jaundice, Neonatal/diagnostic imaging/etiology MH - *Jaundice, Obstructive/complications/etiology MH - Liver/pathology OTO - NOTNLM OT - Causes OT - Imaging OT - Jaundice OT - Pediatric EDAT- 2022/06/03 06:00 MHDA- 2022/08/23 06:00 CRDT- 2022/06/02 11:21 PHST- 2021/07/22 00:00 [received] PHST- 2022/01/25 00:00 [accepted] PHST- 2022/06/03 06:00 [pubmed] PHST- 2022/08/23 06:00 [medline] PHST- 2022/06/02 11:21 [entrez] AID - 10.1007/s12098-022-04171-7 [pii] AID - 10.1007/s12098-022-04171-7 [doi] PST - ppublish SO - Indian J Pediatr. 2022 Sep;89(9):899-907. doi: 10.1007/s12098-022-04171-7. Epub 2022 Jun 2.