PMID- 35654020 OWN - NLM STAT- MEDLINE DCOM- 20220606 LR - 20220627 IS - 1097-4199 (Electronic) IS - 0896-6273 (Linking) VI - 110 IP - 11 DP - 2022 Jun 1 TI - Seq-ing the mechanisms of migraine. PG - 1745-1746 LID - S0896-6273(22)00405-6 [pii] LID - 10.1016/j.neuron.2022.04.028 [doi] AB - The trigeminal ganglia (TG) play a crucial role in migraine pathophysiology. In this issue of Neuron, Yang et al. developed a single-cell atlas profiling the transcriptome and epigenome of mouse and human TG, thus providing a roadmap for therapeutic targeting. CI - Copyright (c) 2022 Elsevier Inc. All rights reserved. FAU - Cropper, Haley C AU - Cropper HC AD - Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA. FAU - Pradhan, Amynah A AU - Pradhan AA AD - Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA. Electronic address: pradhan4@uic.edu. LA - eng PT - Comment PT - Journal Article PL - United States TA - Neuron JT - Neuron JID - 8809320 SB - IM CON - Neuron. 2022 Jun 1;110(11):1806-1821.e8. PMID: 35349784 MH - Humans MH - *Migraine Disorders/genetics MH - Neurons MH - Transcriptome MH - *Trigeminal Ganglion COIS- Declaration of interests A.A.P. has received research contracts from Lundbeck. EDAT- 2022/06/03 06:00 MHDA- 2022/06/07 06:00 CRDT- 2022/06/02 18:29 PHST- 2022/06/02 18:29 [entrez] PHST- 2022/06/03 06:00 [pubmed] PHST- 2022/06/07 06:00 [medline] AID - S0896-6273(22)00405-6 [pii] AID - 10.1016/j.neuron.2022.04.028 [doi] PST - ppublish SO - Neuron. 2022 Jun 1;110(11):1745-1746. doi: 10.1016/j.neuron.2022.04.028.