PMID- 35659441
OWN - NLM
STAT- MEDLINE
DCOM- 20230530
LR  - 20230530
IS  - 2255-534X (Electronic)
IS  - 2255-534X (Linking)
VI  - 88
IP  - 2
DP  - 2023 Apr-Jun
TI  - Interval gastric cancer: A call to attentiveness and action.
PG  - 91-99
LID - S2255-534X(22)00048-2 [pii]
LID - 10.1016/j.rgmxen.2022.05.015 [doi]
AB  - INTRODUCTION AND AIMS: Endoscopy is the most effective method for identifying 
      gastric adenocarcinoma (GAC). Interval gastric cancer (IGC) is GAC that is 
      diagnosed 2-3 years after a normal endoscopy. Its characteristics are unknown in 
      the Colombian environment. The clinical, histopathologic, and endoscopic 
      characteristics were evaluated, along with the presentation rate, proton pump 
      inhibitor (PPI) use, and IGC survival rate, and compared with other types of GAC. 
      METHODS: A retrospective, analytic study was conducted on a prospective cohort. 
      It evaluated 513 patients with GAC treated at our institution, within the time 
      frame of January 2012 and June 2018. The patients had endoscopic diagnosis of GAC 
      and endoscopy within the past three years that was negative for tumor. RESULTS: A 
      total of 513 patients diagnosed with GAC were evaluated. Forty-two of the 
      patients had IGC (8.2%): 9 early lesions and 33 advanced lesions (79%). The IGCs 
      were smaller (31 vs. 41 mm; P < .01), as well as flatter and more depressed 
      (P < .01). There was no association with PPI use, but there was an association 
      with a history of gastrectomy and anastomosis (P = .02), as well as the absence 
      of red flags (P < .003). The most frequent locations were the gastric body (52%) 
      and the antrum (26%). Overall two-year survival was similar between IGC and GAC 
      (37.1 vs. 39.3%, P = .72). CONCLUSION: A total of 8.2% of recently diagnosed GAC 
      were cases of IGC. The presence of anastomosis and the absence of red flags were 
      related to IGC. Overall survival was poor and there were no differences from the 
      other types of GAC detected.
CI  - Copyright (c) 2021 Asociacion Mexicana de Gastroenterologia. Published by Masson 
      Doyma Mexico S.A. All rights reserved.
FAU - Castano-Llano, R
AU  - Castano-Llano R
AD  - Cirugia Gastrointestinal y Endoscopia Clinica las Americas, Medellin, Antioquia, 
      Colombia; Grupo de Gastro-Hepatologia, Universidad de Antioquia, Medellin, 
      Antioquia, Colombia; Instituto de Cancerologia, Clinica las Americas, Medellin, 
      Antioquia, Colombia. Electronic address: rcastanoll@hotmail.com.
FAU - Pineres, A
AU  - Pineres A
AD  - Cirugia Gastrointestinal y Endoscopia Clinica las Americas, Medellin, Antioquia, 
      Colombia; Instituto de Cancerologia, Clinica las Americas, Medellin, Antioquia, 
      Colombia.
FAU - Jaramillo, R
AU  - Jaramillo R
AD  - Instituto de Cancerologia, Clinica las Americas, Medellin, Antioquia, Colombia; 
      Clinica las Americas, Medellin, Antioquia, Colombia.
FAU - Molina, S
AU  - Molina S
AD  - Instituto de Cancerologia, Clinica las Americas, Medellin, Antioquia, Colombia; 
      Clinica las Americas, Medellin, Antioquia, Colombia.
FAU - Aristizabal, F
AU  - Aristizabal F
AD  - Instituto de Cancerologia, Clinica las Americas, Medellin, Antioquia, Colombia; 
      Clinica las Americas, Medellin, Antioquia, Colombia.
FAU - Puerta, J E
AU  - Puerta JE
AD  - Universidad CES, Medellin, Antioquia, Colombia.
LA  - eng
PT  - Journal Article
DEP - 20220531
PL  - Mexico
TA  - Rev Gastroenterol Mex (Engl Ed)
JT  - Revista de gastroenterologia de Mexico (English)
JID - 101778603
SB  - IM
MH  - Humans
MH  - *Stomach Neoplasms/pathology
MH  - Retrospective Studies
MH  - Prospective Studies
MH  - Gastroscopy/methods
OTO - NOTNLM
OT  - Calidad en endoscopia
OT  - Cancer gastrico
OT  - Cancer gastrico de intervalo
OT  - Esofagogastroduodenoscopia
OT  - Esophagogastroduodenoscopy
OT  - Gastric cancer
OT  - Interval gastric cancer
OT  - Quality in endoscopy
OT  - Supervivencia
OT  - Survival
EDAT- 2022/06/07 06:00
MHDA- 2023/05/30 06:42
CRDT- 2022/06/06 10:51
PHST- 2021/04/09 00:00 [received]
PHST- 2021/05/25 00:00 [accepted]
PHST- 2023/05/30 06:42 [medline]
PHST- 2022/06/07 06:00 [pubmed]
PHST- 2022/06/06 10:51 [entrez]
AID - S2255-534X(22)00048-2 [pii]
AID - 10.1016/j.rgmxen.2022.05.015 [doi]
PST - ppublish
SO  - Rev Gastroenterol Mex (Engl Ed). 2023 Apr-Jun;88(2):91-99. doi: 
      10.1016/j.rgmxen.2022.05.015. Epub 2022 May 31.