PMID- 35662515
OWN - NLM
STAT- MEDLINE
DCOM- 20220804
LR  - 20221013
IS  - 1532-8422 (Electronic)
IS  - 1053-0770 (Linking)
VI  - 36
IP  - 9
DP  - 2022 Sep
TI  - Left Ventricular Ejection Fraction Correlation With Stroke Volume as Estimated by 
      Doppler Echocardiography in Cardiogenic Shock: A Retrospective Observational 
      Study.
PG  - 3511-3516
LID - S1053-0770(22)00334-2 [pii]
LID - 10.1053/j.jvca.2022.05.009 [doi]
AB  - OBJECTIVES: Echocardiography is the main tool for cardiac assessment and helps to 
      guide management in patients admitted to the intensive care unit (ICU) with 
      cardiogenic shock (CS). Left ventricular ejection fraction (LVEF) is a commonly 
      used echocardiographic surrogate for left ventricular (LV) systolic function. In 
      this hypothesis-generating study, the authors investigated the correlation 
      between LVEF and stroke volume (SV)/SV index (SVI) estimated by Doppler 
      echocardiography in patients admitted to the ICU with CS and reduced LVEF. DESIGN 
      AND SETTING: This retrospective analysis was performed in a single tertiary 
      cardiac center in London, United Kingdom. PARTICIPANTS: Patients admitted to the 
      ICU over a 34-month period with ST elevation myocardial infarction (STEMI) 
      complicated by CS and LVEF <40%. INTERVENTIONS: Clinical and echocardiographic 
      data were collected. LVEF (total, by visual estimate and by modified Simpson's 
      method) was correlated with SV and SVI estimated by Doppler echocardiography. 
      MEASUREMENTS AND MAIN RESULTS: One-hundred patients were included. The mean age 
      was 62.6 +/- 12.7 years and 78% were male patients. The median LVEF was 29% (20-35) 
      and the mean SV and SVI by Doppler echocardiography were 47 mL +/- 16 and 25 mL +/- 
      9, respectively. Analysis revealed a weak yet statistically significant 
      correlation among LVEF and Doppler SV and SVI (r = 0.44, confidence interval [CI] 
      0.26-0.60, p < 0.0001, r = 0.47, CI 0.28-0.62, p < 0.001, respectively). Visually 
      estimated LVEF (n = 74) correlated weakly with Doppler SV and SVI yet better 
      compared to LVEF by Simpson's method (n = 25) (r = 0.48, CI 0.27-0.65, p < 0.0001 
      and r = 0.49, CI 0.28-0.66, p < 0.0001, respectively, v r = 0.36, CI 0.05-0.67, p 
      = 0.08 and r = 0.37, CI -0.04-0.67, p 0.07, respectively). CONCLUSIONS: There is 
      a weak correlation between LVEF and SV or SVI estimated by Doppler 
      echocardiography in patients admitted to the ICU with STEMI complicated by CS and 
      reduced LVEF. Visually estimated LVEF correlated slightly better with Doppler SV 
      compared to modified Simpson's LVEF.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Lashin, Hazem
AU  - Lashin H
AD  - Adult Critical Care Unit, Barts Heart Centre, St. Bartholomew's Hospital, West 
      Smithfield, London, United Kingdom; William Harvey Research Institute, Barts, and 
      the London school of medicine and dentistry, Queen Mary University of London, 
      Charterhouse square, London, United Kingdom. Electronic address: 
      h.lashin@qmul.ac.uk.
FAU - Olusanya, Olusegun
AU  - Olusanya O
AD  - Adult Critical Care Unit, Barts Heart Centre, St. Bartholomew's Hospital, West 
      Smithfield, London, United Kingdom.
FAU - Smith, Andrew
AU  - Smith A
AD  - Adult Critical Care Unit, Barts Heart Centre, St. Bartholomew's Hospital, West 
      Smithfield, London, United Kingdom; William Harvey Research Institute, Barts, and 
      the London school of medicine and dentistry, Queen Mary University of London, 
      Charterhouse square, London, United Kingdom.
FAU - Bhattacharyya, Sanjeev
AU  - Bhattacharyya S
AD  - William Harvey Research Institute, Barts, and the London school of medicine and 
      dentistry, Queen Mary University of London, Charterhouse square, London, United 
      Kingdom; Cardiology department, Barts Heart Centre, St. Bartholomew's Hospital, 
      West Smithfield, London, United Kingdom.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20220510
PL  - United States
TA  - J Cardiothorac Vasc Anesth
JT  - Journal of cardiothoracic and vascular anesthesia
JID - 9110208
SB  - IM
MH  - Aged
MH  - Echocardiography, Doppler
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - *ST Elevation Myocardial Infarction/complications
MH  - Shock, Cardiogenic/diagnostic imaging
MH  - Stroke Volume
MH  - *Ventricular Function, Left
OTO - NOTNLM
OT  - cardiogenic shock
OT  - echocardiography
OT  - ejection fraction
OT  - left ventricle
OT  - stroke volume
EDAT- 2022/06/07 06:00
MHDA- 2022/08/05 06:00
CRDT- 2022/06/06 13:38
PHST- 2022/02/08 00:00 [received]
PHST- 2022/04/28 00:00 [revised]
PHST- 2022/05/05 00:00 [accepted]
PHST- 2022/06/07 06:00 [pubmed]
PHST- 2022/08/05 06:00 [medline]
PHST- 2022/06/06 13:38 [entrez]
AID - S1053-0770(22)00334-2 [pii]
AID - 10.1053/j.jvca.2022.05.009 [doi]
PST - ppublish
SO  - J Cardiothorac Vasc Anesth. 2022 Sep;36(9):3511-3516. doi: 
      10.1053/j.jvca.2022.05.009. Epub 2022 May 10.