PMID- 35667566
OWN - NLM
STAT- MEDLINE
DCOM- 20221229
LR  - 20221229
IS  - 1878-3554 (Electronic)
IS  - 0099-2399 (Linking)
VI  - 48
IP  - 9
DP  - 2022 Sep
TI  - The Effect of Primary Root Canal Treatment on Dentinal Tubule Penetration of 
      Calcium Silicate-based Sealers during Endodontic Retreatment.
PG  - 1169-1177
LID - S0099-2399(22)00404-6 [pii]
LID - 10.1016/j.joen.2022.05.008 [doi]
AB  - INTRODUCTION: The aim of this study was to evaluate the effect of previous root 
      canal treatment on dentinal tubule penetration of calcium silicate-based sealers 
      during endodontic retreatment and to compare 2 different (commonly used and 
      modified) tubule penetration depth measurement techniques. METHODS: The crowns of 
      mandibular premolar teeth were removed, and root canals were prepared (ProTaper 
      Universal; Dentsply Sirona, York, PA) and obturated using AH Plus (AH; Dentsply 
      DeTrey, Konstanz, Germany), MTA Fillapex (MTAF; Angelus, Londrina, Brazil), and 
      WellRoot ST (WRST; Vericom, Gyeonggi-do, South Korea); 0.1% red Rhod-2 dye 
      (Chemodex, St Gallen, Switzerland) was added to the sealers. After storage for 3 
      weeks (37 degrees C, 100% humid), the following sealer combination subgroups were created 
      (the sealer used during the primary root canal treatment/the sealer used during 
      the retreatment, n = 8): AH/AH, AH/MTAF, and AH/WRST; MTAF/AH, MTAF/MTAF, and 
      MTAF/WRST; and WRST/AH, WRST/MTAF, and WRST/WRST. Green Fluo-3 dye (0.1%) was 
      added to the sealers during retreatment. Sealer penetration depths were measured 
      at 8 points and averaged, and the ratio of the retreatment sealer to the initial 
      sealer was recorded as the mean tubule penetration depth ratio in the first 
      technique, whereas the percentage of the circumferential penetration area ratios 
      of the retreatment and initial sealers was calculated in the second technique. 
      Statistical analyses were performed using Kolmogorov-Smirnov, Kruskal-Wallis, and 
      Mann-Whitney U tests. RESULTS: The mean penetration depth of AH and MTFA was 
      found to be higher at the coronal third region in the control groups (P < .05). 
      Both methods showed a significant difference among the groups at the coronal and 
      median regions (P < .05). The AH/WRST, MTAH/AH, MTAF/MTAF, MTAF/WRSTS, and 
      WRST/WRST groups showed deeper tubule penetration (first technique, P = .01). 
      Both techniques showed that the penetration depth of the sealers was the same at 
      the apical region (P > .05), whereas a difference was found among the techniques 
      at the coronal and median regions. The sealers used in the previous root canal 
      treatment limited the penetration depth of the sealers used during the 
      retreatment process (P < .05). When MTAF was used as the initial sealer, the 
      penetration depth of the second sealer did not change, whereas if WRST was the 
      initial sealer, the penetration depth of the sealers at the median and apical 
      regions is negatively affected during the retreatment process (P < .05). 
      CONCLUSIONS: Previous root canal treatment affects the penetration depth of 
      calcium silicate-based sealers. The use of AH Plus and MTA Fillapex during the 
      retreatment process showed an advantage. Both measurement techniques showed 
      similar performances at the apical region, whereas the results varied at the 
      coronal and midcoronal regions; therefore, a more stable sealer penetration 
      measurement technique is still necessary.
CI  - Copyright (c) 2022 American Association of Endodontists. Published by Elsevier Inc. 
      All rights reserved.
FAU - Egemen, Aysenur
AU  - Egemen A
AD  - Department of Endodontics, Selcuk University, Konya, Turkey.
FAU - Belli, Sema
AU  - Belli S
AD  - Department of Endodontics, Selcuk University, Konya, Turkey. Electronic address: 
      sbelli@selcuk.edu.tr.
LA  - eng
PT  - Journal Article
DEP - 20220603
PL  - United States
TA  - J Endod
JT  - Journal of endodontics
JID - 7511484
RN  - 0 (Calcium Compounds)
RN  - S4255P4G5M (calcium silicate)
RN  - 0 (Epoxy Resins)
RN  - 0 (Root Canal Filling Materials)
RN  - 0 (Silicates)
MH  - Calcium Compounds
MH  - *Dental Pulp Cavity
MH  - Dentin
MH  - Epoxy Resins/pharmacology
MH  - Retreatment
MH  - *Root Canal Filling Materials/pharmacology
MH  - Silicates
OTO - NOTNLM
OT  - AH Plus
OT  - MTA Fillapex
OT  - WellRoot ST
OT  - confocal laser scanning microscopy
OT  - dentinal tubule penetration
OT  - retreatment
EDAT- 2022/06/07 06:00
MHDA- 2022/09/01 06:00
CRDT- 2022/06/06 19:26
PHST- 2022/02/08 00:00 [received]
PHST- 2022/05/22 00:00 [revised]
PHST- 2022/05/26 00:00 [accepted]
PHST- 2022/06/07 06:00 [pubmed]
PHST- 2022/09/01 06:00 [medline]
PHST- 2022/06/06 19:26 [entrez]
AID - S0099-2399(22)00404-6 [pii]
AID - 10.1016/j.joen.2022.05.008 [doi]
PST - ppublish
SO  - J Endod. 2022 Sep;48(9):1169-1177. doi: 10.1016/j.joen.2022.05.008. Epub 2022 Jun 
      3.