PMID- 35672667
OWN - NLM
STAT- MEDLINE
DCOM- 20220609
LR  - 20231101
IS  - 1471-2318 (Electronic)
IS  - 1471-2318 (Linking)
VI  - 22
IP  - 1
DP  - 2022 Jun 7
TI  - Association of body mass index and waist circumference with type 2 diabetes 
      mellitus in older adults: a cross-sectional study.
PG  - 489
LID - 10.1186/s12877-022-03145-w [doi]
LID - 489
AB  - BACKGROUND: The prevalence of obesity and diabetes is rising. The aim of this 
      study was to determine the association of body mass index (BMI) and waist 
      circumference (WC) with type 2 diabetes mellitus (T2DM) in the elderly and to 
      compare the discriminatory abilities of BMI, WC and other anthropometric 
      indicators, including waist-to-height ratio (WHtR), body adiposity estimator 
      (BAE) and body roundness index (BRI) for T2DM. METHODS: This cross-sectional 
      study included 69,388 subjects aged >/= 60 years living in Xinzheng, Henan 
      Province, from January to December 2020. The data came from the residents' 
      electronic health records of the Xinzheng Hospital Information System. Logistic 
      regression was used to examine the relationships. Fully adjusted models adjusted 
      for age, sex, place of residence, alcohol consumption, smoking, physical 
      exercise, SBP and RHR. The area under the receiver operating characteristic curve 
      (AUC) was used to compare the discriminatory ability of different anthropometric 
      indicators for T2DM under the influence of potential risk factors. RESULTS: After 
      adjusting for multiple covariates, compared with the first BMI quintile, the odds 
      ratios (ORs) and 95% confidence intervals (CIs) from the second to fifth quintile 
      for T2DM were 1.416 (1.335-1.502), 1.664 (1.570-1.764), 1.879 (1.774-1.990) and 
      2.156 (2.037-2.283), respectively. Compared with the first WC quintile, the ORs 
      and 95% CIs from the second to fifth quintiles for T2DM were 1.322 (1.244-1.404), 
      1.549 (1.459-1.643), 1.705 (1.609-1.807) and 2.169 (2.048-2.297), respectively. 
      Among men, compared with other anthropometric indicators (BMI, WHtR, BAE and 
      BRI), WC showed the highest AUC (AUC: 0.629; 95% CI: 0.622-0.636). Among women, 
      the AUCs of BMI (AUC: 0.600; 95% CI: 0.594-0.606), WC (AUC: 0.600; 95% CI: 
      0.593-0.606) and BAE (AUC: 0.600; 95% CI: 0.594-0.607) were similar, and the AUCs 
      of BMI, WC and BAE were higher than WHtR, BRI. CONCLUSIONS: All anthropometric 
      indicators were positively associated with T2DM. In men, WC with the strongest 
      positive association with T2DM was the best predictor of T2DM. In women, BMI was 
      most strongly associated with T2DM, and the predictive powers of BMI, WC and BAE 
      were similar. After adjusting the potential confounding factors including age, 
      sex, place of residence, alcohol consumption, smoking, physical exercise, SBP and 
      RHR, the effect of these factors was eliminated, the findings were independent of 
      the covariates considered.
CI  - (c) 2022. The Author(s).
FAU - Bai, Kaizhi
AU  - Bai K
AD  - College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
FAU - Chen, Xuejiao
AU  - Chen X
AD  - College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
FAU - Song, Rui
AU  - Song R
AD  - College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
FAU - Shi, Wenlong
AU  - Shi W
AD  - College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
FAU - Shi, Songhe
AU  - Shi S
AD  - College of Public Health, Zhengzhou University, Zhengzhou, Henan, China. 
      ssh@zzu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220607
PL  - England
TA  - BMC Geriatr
JT  - BMC geriatrics
JID - 100968548
SB  - IM
MH  - Aged
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/complications/diagnosis/epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Obesity/complications/diagnosis/epidemiology
MH  - Risk Factors
MH  - Waist Circumference
MH  - Waist-Height Ratio
PMC - PMC9175364
OTO - NOTNLM
OT  - Anthropometric indicators
OT  - Body mass index
OT  - Older adults
OT  - Type 2 diabetes mellitus
OT  - Waist circumference
COIS- The authors declare that they have no competing interests.
EDAT- 2022/06/08 06:00
MHDA- 2022/06/10 06:00
PMCR- 2022/06/07
CRDT- 2022/06/07 23:38
PHST- 2022/03/22 00:00 [received]
PHST- 2022/05/16 00:00 [accepted]
PHST- 2022/06/07 23:38 [entrez]
PHST- 2022/06/08 06:00 [pubmed]
PHST- 2022/06/10 06:00 [medline]
PHST- 2022/06/07 00:00 [pmc-release]
AID - 10.1186/s12877-022-03145-w [pii]
AID - 3145 [pii]
AID - 10.1186/s12877-022-03145-w [doi]
PST - epublish
SO  - BMC Geriatr. 2022 Jun 7;22(1):489. doi: 10.1186/s12877-022-03145-w.