PMID- 35673825 OWN - NLM STAT- MEDLINE DCOM- 20220609 LR - 20220722 IS - 2066-8279 (Electronic) IS - 1220-0522 (Print) IS - 1220-0522 (Linking) VI - 62 IP - 4 DP - 2021 Oct-Dec TI - Esophageal spindle cell lipoma. PG - 1051-1055 LID - 10.47162/RJME.62.4.18 [doi] AB - Symptomatic ordinary esophageal lipomas are rare tumors. Spindle cell lipomas (SCLs) of this location are even more infrequent. To our knowledge, only a previous esophageal SCL case has been reported. We describe herein the case of a 62-year-old woman with a long history of heartburn and feeling of abdominal distension. Preoperative investigations, including a Barium meal, gastroscopy, and echoendoscopy revealed a lipomatous polypoid mass attached to the middle esophageal segment. The lesion (3.5x2x1 cm) was excised endoscopically under deep sedation. The final histopathology diagnosis was pedunculated SCL. An accurate diagnosis of esophageal SCL is crucial to rule out malignant lesions, relieve symptoms, and undertake suitable treatment. The main differential diagnosis includes well-differentiated sclerosing liposarcoma, atypical spindle cell∕pleomorphic lipomatous tumor, giant fibrovascular polyp, and fat-forming solitary fibrous tumor. Although rare, SCL should be added to the list of lipomatous tumors that can affect the esophagus. Complete excision is the appropriate treatment. FAU - Val-Bernal, Jose Fernando AU - Val-Bernal JF AD - Pathology Unit, Department of Medical and Surgical Sciences, University of Cantabria, Santander, Spain; fernando.val@unican.es. FAU - Mayorga, Marta Maria AU - Mayorga MM FAU - Fontanil, Natalia AU - Fontanil N FAU - Teran, Alvaro AU - Teran A LA - eng PT - Case Reports PT - Journal Article PL - Romania TA - Rom J Morphol Embryol JT - Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie JID - 9112454 SB - IM MH - Diagnosis, Differential MH - *Esophageal Neoplasms/diagnosis/pathology MH - Female MH - Humans MH - *Lipoma/diagnosis/pathology MH - *Liposarcoma/pathology MH - Middle Aged MH - *Polyps PMC - PMC9289690 COIS- The authors declare that they have no conflict of interests. EDAT- 2022/06/09 06:00 MHDA- 2022/06/10 06:00 PMCR- 2021/10/01 CRDT- 2022/06/08 02:53 PHST- 2022/06/08 02:53 [entrez] PHST- 2022/06/09 06:00 [pubmed] PHST- 2022/06/10 06:00 [medline] PHST- 2021/10/01 00:00 [pmc-release] AID - 62042110511055 [pii] AID - 10.47162/RJME.62.4.18 [doi] PST - ppublish SO - Rom J Morphol Embryol. 2021 Oct-Dec;62(4):1051-1055. doi: 10.47162/RJME.62.4.18.